Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2011-07-05
2011-07-05
Salimi, Ali R. (Department: 1649)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C424S198100, C530S350000
Reexamination Certificate
active
07973007
ABSTRACT:
Neuregulin, a known neuroprotein, has been found to ameliorate or prevent damage caused by mechanical or chemical assault to blood vessels and, when administered into the cerebral spinal fluid, can ameliorate damage to neuronal tissue caused by stroke or inflammation. Additionally, neuregulin has been found to be useful for enhancement of stem cell migration from the ventricle to the site of injury to the brain.
REFERENCES:
patent: 5231086 (1993-07-01), Sollevi
patent: 6252051 (2001-06-01), Godowski et al.
patent: 6635249 (2003-10-01), Marchionni et al.
patent: 7795212 (2010-09-01), Zhou
patent: 2003/0199103 (2003-10-01), Shimkets et al.
patent: 2004/0115175 (2004-06-01), Blau et al.
patent: 2006/0200097 (2006-09-01), Humayun et al.
patent: 2005016966 (2005-02-01), None
Ellis et al. (J Am Coll Cardiol 11: 211-216, 1988).
Anton, et al., “Role of GGF
euregulin signaling in interactions between migrating neurons and radial glia in the developing cerebral cortex,” Development, vol. 124, pp. 3501-3510 (1997).
Xu, et al., “Extended therapeutic window and functional recovery after intraarterial administration of neuregulin-1 after focal ischemic stroke,” Journal of Cerebral Blood Flow & Metabolism, pp. 1-9 (2005).
Zhang, et al., “Neurotrophic and neuroprotective effects of the neuregulin glial growth factor-2 on dopaminergic neurons in rat primary midbrain cultures,” Journal of Neurochemistry, vol. 91, pp. 1358-1368 (2004).
International Search Report; Written Opinion of International Searching Authority and International Preliminary Report on Patentability (International Patent Application No. PCT/US2006/034338 filed Sep. 1, 2006).
Albers GW Am J Cardiol. 80(4C): 4D-10D, 1997.
Falls, Expt Cell Res 284: 14-30, 2003.
Michailov et al. Science 304: 700-703, 2004.
Petras, J Expt Anal Behav 61: 319-329, 1994.
Erlich et al. Neurosci 107: 353-362, 2001.
Kamel et al. Environ Health Perspec 112: 950-958, 2004.
Xu et al., J Cereb Blood Flow Metab 26: 527-535, 2006—online publication Aug. 31, 2005.
Carpentier et al. NeuroTox 22: 299-315, 2001.
Clement, C et al., “Neuregulin-1 Attenuates Neointimal Formation following Vascular Injury and Inhibits the Proliferation of Vascular Smooth Muscle Cells”, J. Vasc. Res. (2007); 44:303-312.
Andrews & Kurth LLP
Dutt Aditi
Morehouse School of Medicine
Salimi Ali R.
Wang Ping
LandOfFree
Neuregulins for prevention and treatment of damage from... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Neuregulins for prevention and treatment of damage from..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Neuregulins for prevention and treatment of damage from... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2704683