Neuraminidase treated ancrod

Details Neuraminidase treated ancrod Neuraminidase treated ancrod

1984-12-26

1986-04-29

Rosen, Sam

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

514 8, 514 2, 424 94, 435 68, 435 69, 435219, A61K 3558

Patent

active

045856532

ABSTRACT:
Disclosed is a pharmaceutically effective agent and method of use, comprising ancrod which has been incubated with neuraminidase. The neuraminidase-treated ancrod (NTA) can be substituted for ancrod in ancrod therapy, when immunological resistance to the latter has become manifest. Conversely, NTA can be administered initially, and ancrod substituted therefor after NTA resistance becomes manifest.

REFERENCES:
Chem. Abst.-Chem. Subj. Index-10th Coll., (1977-1981), p. 45007CS.

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