Neural transplantation using pluripotent neuroepithelial cells

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S093200

Reexamination Certificate

active

11178216

ABSTRACT:
The subject invention pertains to a novel method of correction of behavioral and/or psychological deficits made possible by the intracerebral transplantation of pluripotent neuroepithelial cells. Cells, cell lines, pharmaceutical preparations, medicaments, methods for the production and maintenance of the cell lines for use in the method of the invention are encompassed by the invention.

REFERENCES:
patent: 5270191 (1993-12-01), McKay et al.
patent: 5580777 (1996-12-01), Bernard et al.
patent: 5588692 (1996-12-01), Gandhi et al.
patent: 5690927 (1997-11-01), Major et al.
patent: 5753491 (1998-05-01), Major et al.
patent: 5817773 (1998-10-01), Wilson et al.
patent: 5851832 (1998-12-01), Weiss et al.
patent: 5958767 (1999-09-01), Snyder et al.
patent: 6165715 (2000-12-01), Collins et al.
patent: 6197585 (2001-03-01), Stringer
patent: 6200806 (2001-03-01), Thomson
patent: 6399384 (2002-06-01), Jat
patent: 6465215 (2002-10-01), Price et al.
patent: 6528306 (2003-03-01), Snyder et al.
patent: 6569421 (2003-05-01), Hodges
patent: 7048921 (2006-05-01), Sinden et al.
patent: 2001/0001662 (2001-05-01), Sinden et al.
patent: 2002/0028510 (2002-03-01), Sanberg et al.
patent: 2002/0123143 (2002-09-01), Toma et al.
patent: 2002/0146821 (2002-10-01), Sanchez-Ramos et al.
patent: 2003/0108535 (2003-06-01), Hodges
patent: 2003/0147873 (2003-08-01), Sinden et al.
patent: 2003/0203483 (2003-10-01), Seshi
patent: 2005/0032213 (2005-02-01), Sinden et al.
patent: WO 89/03872 (1989-05-01), None
patent: WO 89/09816 (1989-10-01), None
patent: WO 91/09936 (1991-07-01), None
patent: WO 92/11355 (1992-07-01), None
patent: WO 93/01275 (1993-01-01), None
patent: WO 93/18137 (1993-09-01), None
patent: WO 96/15226 (1996-05-01), None
patent: WO 97/10329 (1997-03-01), None
patent: WO 98/07841 (1998-02-01), None
patent: WO 00/50568 (2000-08-01), None
patent: WO 01/21790 (2001-03-01), None
patent: WO 01/66698 (2001-09-01), None
patent: WO 01/94541 (2001-12-01), None
patent: WO 03/000868 (2003-01-01), None
patent: WO 03/029432 (2003-10-01), None
Scheffler, 1999, Trends in Neuroscience, vol. 22, pp. 348-357.
Sinden (1997, Neuroscience, vol. 81, pp. 599-608).
Hodges (1997, Pharm. Biochem. and Behavior, vol. 56, pp. 763-780).
Sanberg (Feb. 1998, Proceedings of the 1998 Miami Biotechnology winter symposium, vol. 38, p. 139-142).
Netto (1993, Behavioral Brain Res., vol. 58, p. 107-112).
Rashid-Doubell (1994, Gene Therapy, vol. 1, Supp. 1, p. S63.
Bartlett (PNAS, 1988, vol. 85, No. 9, p. 3255-3259).
U.S. Appl. No. 09/913,443, filed Aug. 14, 2001, Price.
Allay, J.A. et al. “LacZ and interleukin-3 expression in vivo after retroviral transduction of marrow-derived human osteogenic mesenchymal progenitors”Human Gene Therapy, 1997, 8:1417-1427.
Anderson, W.F. “Human gene therapy”Nature, 1998, 392:25-30.
Cepko, C.L. “Immortalization of neural cells via retrovirus-mediated oncogene transduction”Ann. Rev. Neurosci., 1989, 12:47-65.
Chopp, M. et al. “Adult bone marrow transplantation for treatment of stroke in adult mice”Society for Neuroscience, 1999, 25:1309, abstract No. 528.2 (abstract).
Crystal, R.G. “Transfer of genes to humans: early lessons and obstacles to success”Science, 1995, 270:404-410.
Deonarain, M.P. “Ligand-targeted receptor-mediated vectors for gene delivery”Exp. Opin. Ther. Patents, 1998, 8(1):53-69.
Frederiksen, K. et al. “Immortalization of Precursor Cells from the Mammalian CNS”Neuron, 1988, 1:439-448.
Gray, J.A. et al. “Prospects for the clinical application of neural transplantation with the use of conditionally immortalized neuroepithelial stem cells”Phil. Trans. R. Soc. Lond. B, 1999, 354:1407-1421.
Hodges, H. et al. “Cognitive Deficits Induced by Global Cerebral Ischaemia: Prospects for Transplant Therapy”Pharm. Biochem. and Behavior, 1997, 56(4):763-780.
Jat, P.S. “Direct derivation of conditionally immortal cell lines from anH-2Kb-tsA58 transgenic mouse”Proc. Natl. Acad. Sci. USA, 1991, 88:5096-5100.
Major, E.O. et al. “Establishment of a line of human fetal glial cells that supports JC virus multiplication”Proc. Natl. Acad. Sci. USA, 1985, 82:1257-1261.
McKay et al. “Mechanisms Regulating Cell Number and Type in the Mammalian Central Nervous System” cold Spring Harbor Symposia on Quantitative Biology, 1990, 55:291-301.
McKay et al. “Immortalized Stem Cells Form the Central Nervous System” C.R. Acad. Sci. Paris, Sciences De La Vie, 1993, 316:1452-1457.
Mezey, E. and K.J. Chandross “Bone marrow: a possible alternative source of cells in the adult nervous system”Euro. J. Pharmacology, 2000, 405:297-302.
Miller, N. and R. Vile “Targeted vectors for gene therapy”FASEB J., 1995, 9:190-199.
Netto, C.A. et al. “Foetal grafts from hippocampal regio superior alleviate ischaemie-induced behavioral deficits”Behavioural Brain Res., 1993, 58:107-112.
Okabe et al. “Development of Neuronal Precursor Cells and Functional Postmitotic Neurons from Embryonic Stem Cells in Vitro” Mechanisms of Development, 1996, 59:89-102.
Palu, G. et al. “In pursuit of new developments for gene therapy of human diseases”J. Biotechnology, 1999, 68:1-13.
Rashid-Doubell, F. et al. “Effects of Basic Fibroblast Growth FActor and Gamma Interferon on Hippocampal Progenitor Cells DErived from the H-2Kb-tsA58 Transgenic Mouse”Gene Ther, 1994;1(Suppl 1):S63.
Renfranz, P.J. et al. “Region-Specific Differentiation of the Hippocampal Stem Cell Line HiB5 upon Implantation into the Developing Mammalian Brain”Cell, Aug. 23, 1991, 66:713-729.
Sanberg, P.R. and A.E. Willing “Cellular therapeutic approaches for neurodegenerative disorders” Proceedings of the 1998 Miami Biotechnology Symposium, Feb. 1998, vol. 38, pp. 139-142.
Scheffler, B. et al. “Marrow-mindedness: a perspective on neuropoiesis”Trends Neurosci, 1999, 22:348-357.
Sinden, J.D. et al. “Recovery of spatial learning by grafts of a conditionally immortalized hippocampal neuroepithelial cell line into the ischaemia-lesioned hippocampus”Neuroscience, 1997, 81(3):599-608.
Snyder, E.Y. et al. “Multipotent Neural Cell Lines can Engraft and Participate in Development of Mouse Cerebellum”Cell, Jan. 10, 1992, 68:33-51.
Snyder, E.Y. and J.H. Wolfe “Central nervous system cell transplantation: a novel therapy for storage diseases?”Curr. Opin. Neurol., 1996, 9:126-136.
Snyder, E.Y. et al. “Multipotent neural precursors can differentiate toward replacement of neurons undergoing targeted apoptotic degeneration in adult mouse neocortex”Proc. Natl. Acad. Sci., Oct. 14, 1997, 94(21):11663-11668.
Stem Cells: Scientific Progress and Future Research Directions, Jun. 2001, Introductory Chapter and Chapters 8 and 11.
Verma, I.M. and N. Somia “Gene therapy—promises, problems and prospects”Nature, Sep. 18, 1997, 389:239-242.
Villa, A. et al., “Establishment and properties of a growth factor-dependent, perpetual neural stem cell line from the human CNS” 2000, 161:67:84.
Virley, D. et al. “Primary CA1 and conditionally immortal MHP36 cell grafts restore conditional discrimination learning and recall in marmosets after excitotoxic lesions of the hippocampal CA1 field”Brain, 1999, 122:2321-2335.
White, L.A. and S.R. Whittemore “Immortalization of Raphe Neurons: an Approach to Neuronal Function in vitro and in vivo”J. Chem. Neuroanatomy, 1992, 5:327-330.
Whittemore, S.R. et al. “Isolation and characterization of conditionally immortalized astrocyte cell lines derived from adult human spinal cord”Glia, Mar. 1994, 10:221-226.
Wyllie, F.S. et al. “A phenotypically and karyotypically stable human thyroid epithelial line conditionally immortalized by SV40 large T antigen”Cancer Res., 1992, 52:2938-2945.
Chen, J. et al. “Intravenous Administration of Human Umbilical Cor

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Neural transplantation using pluripotent neuroepithelial cells does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Neural transplantation using pluripotent neuroepithelial cells, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Neural transplantation using pluripotent neuroepithelial cells will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3930123

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.