Neural regeneration using human bone morphogenetic proteins

Details Neural regeneration using human bone morphogenetic proteins Neural regeneration using human bone morphogenetic proteins

1995-05-05

1998-05-26

Allen, Marianne P.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

606152, 424422, 424423, A61K 3818

Patent

active

057564574

ABSTRACT:
Methods and devices are disclosed for inducing growth of neural cells, and repairing neural defects in a mammal. The method comprises administering to said mammal at the site of neural defect, damage or depletion, an effective amount of a bone morphogenetic protein, either in admixture with a pharmaceutically acceptable vehicle, or adsorbed to a suitable matrix. The device comprises bone morphogenetic protein, optionally in combination with other factors, adsorbed on a suitable matrix and contained within an artificial nerve replacement vessel.

REFERENCES:
patent: 4868161 (1989-09-01), Roberts
patent: 4920962 (1990-05-01), Proulx
patent: 4955892 (1990-09-01), Daniloff et al.
patent: 4963146 (1990-10-01), Li
patent: 5292802 (1994-03-01), Rhee et al.
patent: 5306307 (1994-04-01), Senter et al.
patent: 5308889 (1994-05-01), Rhee et al.
patent: 5328955 (1994-07-01), Rhee et al.
D'Alessandro, J. et al., Growth Factors, 11:53-69, 1994.
A. Bignami et al., Brain Research 43:429-435 (1972).
J.R. Fallon, J. of Cell Biology, 100: 198-207 (Jan. 1985).
Michel Kliot et al., Experimental Neurology, 109: 57-69 (1990).
Leu-Fen H. Lin et al., Science, 260: 1130-1132 (May 21, 1993).
Eldon E. Geisert Jr. et al., Developmental Biology, 143: 335-3455 (1991).
R. Goodman, "Methods for Serum-Fee Culture of Neuronal and Lymphoid Cells", 23-36 (1984).
Mark Noble et al., J. of Neuroscience, 4: No. 7 1892-1903 (1984).
G. Perides et al., J. Biological Chemistry, 269: No. 1 765-770 (Jan. 7, 1994).
George M. Smith et al., Brain Research, 543: 111-122 (1991).

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