Neural cell protein marker RR/B and DNA encoding the same

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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536 235, 435 691, 4353201, 435325, 4352523, C12Q 168, C07H 2104

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active

060664517

ABSTRACT:
The invention contemplates the novel neural cell protein marker RR/B, cDNA encoding RR/B, nucleic acid probes for detection of mRNA encoding RR/B, synthetic polypeptides whose sequences correspond to a portion of RR/B and have a molecular weight equal to less than that of RR/B antibodies specific for RR/B, and methods for detection of RR/B.

REFERENCES:
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Adams, M. et al., "3,400 New Expressed Sequence Tags Identify Diversity of Transcripts in Human Brain", Nature Genetics, vol. 4, pp. 256-267 (1993).
Arnheiter, H. et al., "Physicochemical and Antigenic Properties of Synthetic Fragments of Human Leukocyte Interferon", Nature, vol. 294, pp. 278-280 (1981).
Bantle, J. et al., "Complexity and Characterization of Polyadenylated RNA in the Mouse Brain", Cell, vol. 8, pp. 139-150 (1976).
Guillemin, R., "Peptides in the Brain: The New Endocrinology of the Neuron", Science, vol. 202, pp. 390-402 (1978).
Hastie, N. et al., "The Expression of Three Abundance Classes of Messenger RNA in Mouse Tissues", Cell, vol. 9, pp. 761-774 (1976).
Purves, D. et al.,Principles of Neural Development, Publised by Sinauer Associates Inc., pp. 263-267 (1985).
Sambrook, J. et al.,Molecular Cloning, A Laboratory Manual, Published by Cold Spring Harbor Laboratory Press, Chapter 16, pp. 16.2-16.81 (1989).

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