Neural calcium-activated neutral proteinase inhibitors

Details Neural calcium-activated neutral proteinase inhibitors Neural calcium-activated neutral proteinase inhibitors

1991-07-25

1994-08-23

Hill, Jr., Robert J.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

435 691, C07K 700

Patent

active

053409221

ABSTRACT:
This invention is directed to two highly purified neural calcium-activated neutral proteinase (CANP or calpain) inhibitors, known as high molecular weight calpastatin (HMWC) and low molecular weight calpastatin (LMWC). The invention also relates to recombinant DNA molecules which code for, and antibodies which bind to these proteins. The present invention is further directed to the use of these calpastatin proteins.

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