NES-1 polypeptides, DNA, and related molecules and methods

Details NES-1 polypeptides, DNA, and related molecules and methods NES-1 polypeptides, DNA, and related molecules and methods

1995-06-06

1998-04-07

Wax, Robert A.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

530350, 435212, 435219, 435226, C12N 950

Patent

active

057363773

ABSTRACT:
The expression and purification of normal epithelial specific polypeptide (NES1) which is expressed in normal cells, but not in radiation transformed cells, are described. Both the DNA sequence encoding the NES1 and the corresponding amino acid sequence are disclosed. Also, disclosed are methods for carcinoma detection and treatment using the NES1 as well as methods of identifying compounds modulating the expression and activity of NES1.

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