Nerve growth factor peptides

Details Nerve growth factor peptides Nerve growth factor peptides

1991-01-14

1992-07-28

Cashion, Jr., Merrell C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 15, 514 16, 514 17, 514 18, 530326, 530327, 530328, 530329, 530330, 530839, 930120, 930DIG800, C07K 706, C07K 708, A61K 3702

Patent

active

051341212

ABSTRACT:
The present invention provides both agonist and antagonist nerve growth factor peptides. The NGF blocking peptides can be used to inhibit the expression of mRNA and their encoded proteins whose expression is stimulated by NGF, such as .beta.-protein precursor and prion proteins, which proteins or their products are associated with neurodegenerative disorders, whereas the NGF agonist peptides can be used to treat neoplastic disorders such as neuroblastomas.

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