Nerve gas antidote

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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424406, 424408, 424456, 424464, 424468, 514411, 514415, 514317, 514327, 514520, 514823, 514351, 514534, A61K 3155, A61K 3140, A01N 2532

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active

054300304

ABSTRACT:
A prophylactic pretreatment for nerve gas and pesticide poisons which can be administered orally and which comprises the following agents, in combination: a. Pyridostigmine (pyridostigmine bromide) b. Diazepam c. N-methyl-4-pipyridinyl phenylcyclopentanecarboxylate
These agents may be administered in the form of a capsule which contains, for example, tablets, one a normal release dosage form and one or two in a slow release dosage form.

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Fundam. Appl. Toxicol., vol. 5, No. 6, Pt. 2, pp. S225-S231, 1985, Leadbeater, L., "Treatment of Poisoning by Soman".
Chemical Abstracts, vol. 92, p. 156, No. 16490v, 1980, Davoson, R. M., "Some Adjuncts to Oxime-Atropine . . . ".
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SB Ved Lek Fak Karlovy Univerzity Hradci Kralove, 1991, vol. 34, No. 3, pp. 243-247, Patocka, J. et al., "Efficacy of Various Pretreatment and Therapy Regimens Against Soman Lethality in Mice".
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