Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1993-12-15
1995-07-04
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
424406, 424408, 424456, 424464, 424468, 514411, 514415, 514317, 514327, 514520, 514823, 514351, 514534, A61K 3155, A61K 3140, A01N 2532
Patent
active
054300304
ABSTRACT:
A prophylactic pretreatment for nerve gas and pesticide poisons which can be administered orally and which comprises the following agents, in combination: a. Pyridostigmine (pyridostigmine bromide) b. Diazepam c. N-methyl-4-pipyridinyl phenylcyclopentanecarboxylate
These agents may be administered in the form of a capsule which contains, for example, tablets, one a normal release dosage form and one or two in a slow release dosage form.
REFERENCES:
J. Pharm. Pharmcol., vol. 29, No. 1., 1977, pp. 62-64, CODEN:ISSN:JPPM, Green, D. M. et al., "Dual Mechanism of the Antidotal Action . . . ".
J. Pharm. Pharmacol., vol. 42, No. 4, pp. 247-251, 1990, Karlsson, B. et al., "On the Use of Diazepam and Pro . . . ".
Toxicology, vol. 27, No. 1, pp. 41-54, 1983, Klemm, W. R. "Efficacy and Toxicity of Drug Combinations . . . ".
Chemical Abstracts, vol. 104, No. 13, Mar. 31, 1986, No. 103801, Leadbeater, L. et al., "Treatment of Poisoning by Soman".
Fundam. Appl. Toxicol., vol. 5, No. 6, Pt. 2, pp. S225-S231, 1985, Leadbeater, L., "Treatment of Poisoning by Soman".
Chemical Abstracts, vol. 92, p. 156, No. 16490v, 1980, Davoson, R. M., "Some Adjuncts to Oxime-Atropine . . . ".
Chemical Abstracts, vol. 85, p. 123, No. 57639z, 1976, O'Leary, J. F., "A Comparative Evaluation of Atropine . . . ".
SB Ved Lek Fak Karlovy Univerzity Hradci Kralove, 1991, vol. 34, No. 3, pp. 243-247, Patocka, J. et al., "Efficacy of Various Pretreatment and Therapy Regimens Against Soman Lethality in Mice".
Pharmacol. Toxicol., vol. 67, No. 1, pp. 27-35, 1990, Bataillard, A. et al. "Cardiovascular Consequences of Organo-. . . ".
Holm Bleyer
Sommer Armin
Arzneimittelwerk Dresden GmbH
Cintins Marianne M.
Criares T. J.
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