Nephelometric immunoassay and nephelometer

Details Nephelometric immunoassay and nephelometer Nephelometric immunoassay and nephelometer

1981-08-18

1983-08-30

Punter, William H.

Optics: measuring and testing

By particle light scattering

With photocell detection

356343, 356442, 436805, G01N 2151, G01N 2175, G01N 3348

Patent

active

044013876

ABSTRACT:
A nephelometric immunoassay and a nephelometer therefore, characterized in that light is projected on a sample to-be-measured containing an antigen-antibody complex, that at least two light scattering intensities at different angles with respect to the incident light are measured, and that a true antigen concentration is discriminated by comparing the light scattering intensities.

REFERENCES:
patent: 3714444 (1973-01-01), Carr et al.
patent: 4157871 (1979-06-01), Anderson et al.
patent: 4164558 (1979-08-01), Schulthess et al.
patent: 4174952 (1979-11-01), Cannell et al.
patent: 4268171 (1981-05-01), Sternberg
Buffone et al. "Evaluation of Kinetic Light Scattering as an Approach to the Measurement of Specific Proteins with the Centrifugal Analyzer 11 Theoretical Considerations", Clin. Chem. vol. 21, #12, 1975, pp. 1735-1746.

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