Nephelometric determination of HB.sub.s antigen with antibody-co

Details Nephelometric determination of HB.sub.s antigen with antibody-co Nephelometric determination of HB.sub.s antigen with antibody-co

1985-01-30

1987-09-01

Marantz, Sidney

Chemistry: analytical and immunological testing

Involving antibody fragments

435 5, 435 7, 435810, 436517, 436533, 436534, 436548, 436805, 436808, 436820, 526312, 526315, 935110, G01N 33546, G01N 33547, G01N 33576

Patent

active

046909060

ABSTRACT:
The present invention relates to polyfunctional hydrophilic spherical microparticles of uniform size which contain from 5 to 95% of units originating from the copolymerization of an aldehyde of the formula ##STR1## R.sub.1 being an alkyl radical, from 5 to 90% of units originating from the copolymerization of an acrylic acid ester of the formula ##STR2## in which R.sub.2 is H or alkyl and R.sub.3 is a hydroxyalkyl group, less than 15% of units originating from an acrylic acid derivative chosen from amongst ##STR3## R.sub.4, R.sub.5 and R.sub.6 being alkyl radicals, and from 0.1 to 10% of units originating from a crosslinking product.
The invention also relates to a process for the preparation of the said microparticles and to the use of these microparticles for the nephelometric determination of HB.sub.s antigen.

REFERENCES:
patent: 3553310 (1971-01-01), Csizmas
patent: 3957741 (1976-05-01), Rembaum
patent: 3985632 (1976-10-01), Rembaum
patent: 3992517 (1976-11-01), Lowke
patent: 4046720 (1977-09-01), Rembaum
patent: 4093602 (1978-06-01), Kalal
patent: 4189464 (1980-02-01), Blumberg
patent: 4305925 (1981-12-01), Kapmeyer
patent: 4413070 (1983-11-01), Rembaum
patent: 4438239 (1984-03-01), Rembaum

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