Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1976-02-19
1978-08-08
Daus, Donald G.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
424274, 195DIG7, 195113, C07D48714, C12B 108, C12D 916
Patent
active
041056582
ABSTRACT:
There are disclosed two new antibiotics formerly denominated MC916-A and MC916-B and now called neothramycin A and neothramycin B which are potent inhibitors of the growth of leukemia cells, e.g. Leukemia L-1210 cells in mice. They are produced by controlled fermentation of Streptomyces FERM-P 2452 (A.T.C.C. 31123).
REFERENCES:
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Umezama, Ed. "Index of Antibiotics from Actinomycetes", University Park Press, State College, Penna, 1967, p. 142.
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Brazhinikova et al., J. Antibiotics 25, 668-673 (1972).
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Hamada Masa
Ishizuka Masaaki
Kondo Shin-ichi
Naganawa Hiroshi
Takeuchi Tomio
Berch Mark L.
Daus Donald G.
Taylor, Jr. Herbert W.
Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai
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