Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2004-01-26
2008-05-27
Yu, Misook (Department: 1642)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007230
Reexamination Certificate
active
07378247
ABSTRACT:
The present invention features novel polypeptides and methods of using these polypeptides in the diagnosis, detection, monitoring, and treatment of neoplasms in a mammal, e.g., a human.
REFERENCES:
patent: WO 00/37489 (2000-06-01), None
patent: WO 00/37489 (2000-06-01), None
patent: WO 03/011907 (2003-02-01), None
patent: WO 03/011907 (2003-02-01), None
patent: WO 03/076472 (2003-09-01), None
patent: WO 2004/005351 (2004-01-01), None
Hensel et al, Cancer Research 59:5299-5306, 1999.
Applemelk et al., “Molecular Mimicry betweenHelicobacter pyloriand the Host,”Trends in Microbiology5(2):70-73 (1997).
Burrus et al., “Identification of Cysteine-Rich Receptor for Fibroblast Growth Factors,”Molecular and Cellular Biology12(12):5600-5609 (1992).
Brändlein et al., “Human Monoclonal IgM Antibodies with Apoptotic Activity Isolated from Cancer Patients,”Hum. Antibodies11(4):107-119 (2002).
Brändlein et al., “Natural IgM Antibodies and Immunosurveillance Mechanisms Against Epithelial Cancer Cells in Humans,”Cancer Res. 63:7995-8005 (2003).
Brändlein et al., “Cysteine-Rich Fibroblast Growth Factor Receptor 1, a New Marker for Precancerous Epithelial Lesions Defined by the Human Monoclonal Antibody PAM-1,”Cancer Research63:2052-2061 (2003).
Brändlein et al., “CFR-1 Receptor as Target for Tumor-Specific Apoptosis Induced by the Natural Human Monoclonal Antibody PAM-1,”Oncology Reports11:777-784 (2004).
Brown and Gatter, “Ki67 Protein: the Immaculate Deception,”Histopathology40:2-11 (2002).
Claeys et al., “The Gastric H+, K+—ATPase Is a Major Autoantigen in ChronicHelicobacter pyloriGastritis with Body Mucosa Atrophy,” Gastroenterology 115:340-347 (1998).
Crabtree et al., “Gastric Interleukin-8 and IgA IL-8 Autoantibodies inHelicobacter pyloriInfection,” Scand.J. Immunol. 37:65-70 (1993).
Endl and Gerdes, “The Ki-67 Protein: Fascinating Forms and an Unknown Function,”Experimental Cell Research257:231-237 (2000).
Gonatas et al., “Truncations of the C-Terminal Cytoplasmic Domain of MG160, a Medial Golgi Sialoglycoprotein, Result in its Partial Transport to the Plasma Membrane and Filopodia,”Journal of Cell Science111:249-260 (1998).
Hensel et al., “Mitogenic Autoantibodies inHelicobacter pylori-Associated Stomach Cancerogenesis,”Int. J. Cancer081:229-235 (1999).
Hensel et al., “A Novel Proliferation-Associated Variant of CFR-1 Defined by a Human Monoclonal Antibody,”Lab Invest. 81(8):1097-1108 (2001).
Hensel et al., “A New Variant of Cystein-Rich FGF Receptor (CFR-1) Specifically Expressed on Tumor Cells,”Proceedings of the American Association for Cancer Research Annual41 pp. 698 Abstract 4438 (2000).
Ma et al., “Positive Correlation between H,K-Adenosine Triphosphatase Autoantibodies andHelicobacter pyloriAntibodies in Patients with Pernicious Anemia,”Scand. J. Gastroenterol. 29(11):961-965 (1994).
Mourelatos et al., “Cloning and Sequence Analysis of the Human MG160, a Fibroblast Growth Factor and E-Selectin Binding Membrane Sialoglycoprotein of the Golgi Apparatus,”DNA and Cell Biology15:1121-1128 (1996).
Negrini et al., “Antigenic Mimicry betweenHelicobacter pyloriand Gastric Mucosa in the Pathogenesis of Body Atrophic Gastritis,”Gastroenterology111:655-665 (1996).
Pfaff et al., “Human Monoclonal Antibody against a Tissue Polypeptide Antigen-Related Protein from a Patient with a Signet-Ring Cell Carcinoma of the Stomach,”Cancer Research50:5192-5198 (1990).
Ramires et al., “Ki67 Labelling Index in Gastric Carcinomas. An Immunohistochemical Study Using Double Staining for the Evaluation of the Proliferative Activity of Diffuse-Type Carcinomas,”Journal of Pathology. 182:62-67 (1997).
Scholzen and Gerdes, “The Ki-67 Protein: From the Known and the Unknown,”Journal of Cellular Physiology182:311-322 (2000).
Smalheiser “Proteins in Unexpected Locations,”Molecular Biology of the Cell7:1003-1014 (1996).
Steegmaier et al., “The E-Selectin-Ligand ESL-1 Is a Variant of a Receptor for Fibroblast Growth Factor,”Nature373:615-620 (1995).
Steegmaier et al., “The E-Selectin-Ligand ESL-1 Is Located in the Golgi as well as on Microvilli on the Cell Surface,”Journal of Cell Science110:687-694 (1997).
Steininger et al., “Apoptosis in Chronic Gastritis and its Correlation with Antigastric Autoantibodies,”VirchowsArch 433:13-18 (1998).
Stieber et al., “MG160, A Membrane Protein of the Golgi Apparatus which Is Homologous to a Fibroblast Growth Factor Receptor and to a Ligand for E-Selectin, Is Found only in the Golgi Apparatus and Appears early in Chicken Embryo Development,”Experimental Cell Research219:562-570 (1995).
Stulle et al., “Human Stomach Carcinoma-Specific T Cells Derived from the Tumour-Draining Lymph Nodes,” Br. J. Cancer 70:1053-1059 (1994).
Vollmers et al., “Monoclonal Antibodies NORM-1 and NORM-2 Induce more Normal Behavior of Tumor Cells In Vitro and Reduce Tumor Growth In Vivo,”Cell40:547-557 (1985).
Vollmers et al., “Human Monoclonal Antibodies from Stomach Carcinoma Patients React withHelicobacter pyloriand Stimulate Stomach Cancer Cells in Vitro,”Cancer74(5):1525-1532 (1994).
Vollmers et al., “Adjuvant Therapy for Gastric Adenocarcinoma with the Apoptosis-Inducing Human Monoclonal Antibody SC-1: First Clinical and Histopathological Results,”Oncology Reports5:549-552 (1998).
Vollmers et al., “Nature's Best Weapons to Fight Cancer. Revival of Human Monoclonal IgM Antibodies,”Human Antibodies11:131-142 (2002).
Vollmers and Birchmeier, “Monoclonal Antibodies Inhibit the Adhesion of Mouse B 16 Melanoma Cells in vitro and Block Lung Metastasis in vivo,”Proc. Natl. Acad. Sci. 80:3729-3733 (1983).
Zuber et al., “Cysteine-Rich FGF Receptor Regulates Intracellular FGF-1 and FGF-2 Levels,”Journal of Cellular Physiology170:217-227 (1997).
Vollmers, et al., “PAM-1, a Human Monoclonal IGM Antibody Usefull for Diagnosis and Therapy of Precancerous and Cancerous Epithelial Lesions,” Human Antibodies 11:3-7 (2002) (Sep. 16, 2002 Session Abstract).
Gonatas, et al., “MG-160, a Membrane Sialoglycoprotein of the Medial Cisternae of the Rat Golgi Apparatus, Binds Basic Fibroblast Growth Factor and Exhibits a High Level of Sequence Identity to a Chicken Fibroblast Growth Factor Receptor,”Journal of Cell Science108:457-467 (1995).
GenBank Accession No. AAB06460.
GenBank Accession No. AAB02178.
U.S. Appl. No. 10/586,229, filed Jul. 19, 2006, Vollmers et al.
International Search Report for PCT/IB2005/002480 (Nov. 17, 2005).
Hensel Frank
Müller-Hermelink Hans Konrad
Vollmers Heinz Peter
Clark & Elbing LLP
Debiovision Inc.
Halvorson Mark
Yu Misook
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