Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active... – Polymer from ethylenic monomers only
Patent
1993-05-17
1995-02-14
Kishore, G. S.
Drug, bio-affecting and body treating compositions
Solid synthetic organic polymer as designated organic active...
Polymer from ethylenic monomers only
424 7808, 514 2, A61K 3174
Patent
active
053893662
ABSTRACT:
A composition for oral administration to cancer patients includes a neocarzinostatin derivative and from 0.1 and 100 ml per mg of the neocarzinostatin derivative of at least one fatty acid glyceride which has from 6 to 20 carbon atoms and which is noniodized. The composition is effective in the treatment of cancer by oral administration, including a solid cancerous tumor.
REFERENCES:
patent: 3085994 (1963-04-01), Muskat
patent: 3121043 (1964-02-01), Tobin et al.
patent: 3245933 (1966-04-01), Muskat
patent: 3334022 (1967-08-01), Ishida et al.
patent: 4156719 (1979-05-01), Sezaki et al.
patent: 4182752 (1980-01-01), Maeda et al.
patent: 4659696 (1987-04-01), Hirai et al.
patent: 4670419 (1987-06-01), Uda et al.
patent: 4758580 (1988-07-01), Numasaki et al.
patent: 5026772 (1991-06-01), Kobayashi et al.
Chemical Abstracts, 89:209295d, Neocarzinostatin Derivatives, H. Maeda et al., vol. 89, DE OS 2,813,017.
Chemical Abstracts, 97:272t, vol. 97, 1982, "In Vitro Mode of Action, Pharmacokinetics . . . ", J. Takeshita, et et al., Gann (1982), 73(2), 278-84, p. 26.
Chemical Abstracts, 98:137338j, vol. 98, 1983, "Augumentation of Tumoritropicity . . . ", H. Maeda et al., Igaku no Ayumi (1983), 124(1), 25-8.
Chemical Abstracts, 91:162995j, vol. 91, 1979, "A Lipophilic Derivative of Neocarzinostation . . . ", H. Maeda et al., Int. J. Pept. Protein Res., 1979, 14(2), 81-7, (Eng.).
Wilson, C. O., et al., Eds.. Textbook of Organic Medicinal and Pharmaceutical Chemistry, 7th Ed., J. B. Lippincott Co., Pub., pp. 336-339, (1977).
Iwai, K. et al., "Use of Oily Contrast Medium For Selective Drug Targeting . . . ", Cancer Research, 44, pp. 2115-2121 (May 1984).
Meienhofer, J., Ed., "Primary Structure of Neocarzinostatin, An Antitumor Protein", Science, vol. 178, (Nov. 24, 1972), pp. 875-876.
Ishida, N., et al., "Neocarzinosstatin, An Antitumor Antibiotic of High Molecular Weight", The Journal Of Antibiotics, Ser. A, vol. XVIII, No. 2, (Mar. 1965), pp. 68-76.
Miziorko, H., et al., "Spinach Leaf Phosphoenolpyruvate Carboxylase: Purification . . . ", Archives of Biochemistry and Biophysics, vol. 163, (1974), pp. 378-389.
Maeda Hiroshi
Oka Kiichiro
Suzuki Fujio
Tanaka Shohei
Kayaku Antibiotics Research Co., Ltd.
Kishore G. S.
Kuraray Co. Ltd.
Maeda Hiroshi
Yamanouchi Pharmaceutical Co. Ltd.
LandOfFree
Neocarzinostatin derivative composition for oral administration does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Neocarzinostatin derivative composition for oral administration, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Neocarzinostatin derivative composition for oral administration will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-285985