Nematode fatty acid desaturase-like sequences

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase

Reexamination Certificate

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C435S004000, C435S069520, C435S183000, C435S069100, C435S071100, C435S440000, C435S025000, C435S252300, C435S320100, C536S023200

Reexamination Certificate

active

07993894

ABSTRACT:
Nucleic acid molecules from nematodes encoding fatty acid desaturase polypeptides are described. Fatty acid desaturase-like polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of fatty acid desaturase-like nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators of fatty acid desaturase-like polypeptides, as well as methods for antibody production.

REFERENCES:
patent: 6194167 (2001-02-01), Browse et al.
Guo et al. Proc Natl Acad Sci USA. Jun. 22, 2004;101(25):9205-10.
Branden et al. Introduction to Protein Structure, Garland Publishing Inc., New York, p. 247, 1991.
GenBank Accession No. AAF63745; GI: 7546993; Peyou-Ndi et al., Apr. 13, 2000.
GenBank Accession No. AW783527; GI: 7798133; McCarter et al., May 10, 2001.
GenBank Accession No. AW871151; GI: 8005204; McCarter, May 10, 2001.
GenBank Accession No. BE579346; GI: 9830288; McCarter, May 9, 2001.
GenBank Accession No. NP—068373; GI: 13375616; Marquardt et al., Aug. 4, 2001.
GenBank Accession No. NP—037534; GI: 11181775; Stohr et al., Jan. 15, 2003.

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