Nematode-active toxin from a Bacillus thuringiensis isolate

Details Nematode-active toxin from a Bacillus thuringiensis isolate Nematode-active toxin from a Bacillus thuringiensis isolate

1993-07-27

1994-06-21

Wax, Robert A.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

43525233, 424 93L, 536 2371, C07K 1504, A01N 6302

Patent

active

053229320

ABSTRACT:
A novel B.t. gene encoding a toxin which is toxic to nematodes has been cloned from a B. thuringiensis microbe. The DNA encoding the B.t. toxin can be used to transform various prokaryotic and eukaryotic microbes to express the B.t. toxin. These recombinant microbes can be used to control nematodes in various environments.

REFERENCES:
Prichard, R. K., C. A. Hall, J. D. Kelly, I. C. A. Martin, and A. D. Donald (1980) "The Problem of Anthelmintic Resistance in Nematodes" Australian Veterinary Journal 56:239-251.
Bottjer, Kurt P., Leon W. Bone, and Sarjeet S. Gill (1985) "Nematoda: Susceptability of the Egg to Bacillus thuringiensis Toxins" Experimental Parasitology 60:239-244.
Ignoffo, C. M., and V. H. Dropkin (1977) "Deleterious Effects of the Thermostable Toxin of Bacillus thuringiensis on Species of Soil-Inhabiting, Myceliophagus, and Plant-Parasitic Nematodes" Journal of the Kansas Entomological Society 50(3):394-398.
Ciordia, H., and W. E. Bizzell (1961) "A Preliminary Report on the Effects of Bacillus thuringiensis var. thuringiensis Berliner on the Developments of the Free-Living Stages of Some Cattle Nematodes" Journal of Parisitology 47:41 (abstract).
Coles, G. C. (1986) "Anthelmintic Resistance in Sheep" Parasites: Epidemiology and Control 2(2):423-432.
Prefontaine et al., Appl. & Environ. Microb., Dec. 1987, vol. 53, No. 12, pp. 2808-2814.
Wabiko et al., DNA, vol. 5, No. 4, 1986, pp. 305-314.
Aronson et al., Microb. Rev. vol. 50, No. 1, Mar. 1986, pp. 1-24.
Honigman et al., Gene, vol. 42, 1986, pp. 69-77.

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