Neisseria-specific DNA probe

Details Neisseria-specific DNA probe Neisseria-specific DNA probe

1990-05-31

1992-11-10

Wax, Robert A.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 91, 435177, 435822, 435871, 536 27, 935 78, 935 88, C12G 168, C12P 1934, C12N 1102, C07H 1512

Patent

active

051621991

ABSTRACT:
A Neisseria-specific DNA probe is chosen from the group of the oligonucleotides Opa 1, Opa 2, Opa 3, P III, Pil 1, IgA 1 and IgA 2 or from sequences complementary to these and it can have up to 5 further nucleotides at the 5' and/or 3' end. The probe is suitable for the detection of at least one of the pathogenic Neisseria species N. gonorrhoeae and N. meningitidis under hybridization conditions by the detection of the hybrid formation.

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patent: 4900659 (1990-02-01), Lo et al.
patent: 5047523 (1991-09-01), Woods et al.
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Dinegan et al. Mol. and Cell Probes 3:13 (1989).
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Stern et al. Cell 37:447-56 (1984).

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