Neisseria meningitidis compounds and anti-infection...

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

Reexamination Certificate

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C435S069100, C435S069700, C435S252300, C530S300000, C530S350000, C424S249100, C424S190100, C424S184100, C536S023100, C536S023700

Reexamination Certificate

active

10845424

ABSTRACT:
The invention provides novelNeisseria meningitides(Nm) polypeptides and polynucleotides which cover the Nm genetic diversity, and which correspond to polypeptide of Nm outer membrane and/or periplasma, and to methods for producing such Nm compounds. Also provided are anti-Nm infection, and particularly diagnostic. prophylactic and therapeutic uses thereof.

REFERENCES:
patent: WO 90 04641 (1990-05-01), None
patent: WO 90 06696 (1990-06-01), None
patent: WO 92 03467 (1992-03-01), None
patent: WO 94 05326 (1994-03-01), None
patent: WO 97 28273 (1997-08-01), None
Bowie et al (Science, 1990, 257:1306-1310); Roitt et al (Immunology, 1993, Mosby, St. Louis, p. 7.7-7.8.
Herbert et al (The Dictionary of Immunology, Academic Press, 3rd Edition, London, 1985, pp. 58-59).
Accession: B81989 Parkhill Nature 404, 502-506, 2000.
Holmes (Exp. Opin.Invest. Drugs, 2001, 10(3):511-519).
Nassif et al, “What do we know about the entry ofNeisseria meningitidisinto the meninges?”, Bull. Ins. Pasteur, vol. 95, No. 4, 1997, pp. 219-235.
Ala'Aldeen, “Vaccines AgainstNeisseria meningitidis: Past, Present and Future”, Biotecnologia Aplicada, vol. 13, No. 1, 1996, pp. 1-7.
Gomez et al, “Antigenicity, cross-reactivity and surface exposure of theNeisseria meningitidis37 kDa protein (Fbp)”, Vaccine, vol. 14, No. 14, 1996, pp. 1340-1346.
Sarkari et al, “Variable expression of the Opc outer membrane protein inNeisseria meningitidisis caused by size variation of a promoter containing poly-citidine”, Molecular Microbiology, vol. 13, No. 2, 1994, pp. 207-217.
Maiden et al, “Multilocus sequence typing: a portable approach to the identification of clones within populations of pathogenic microorganisms” Proc. Natl. Acad. Sci. USA, vol. 95, Mar. 1998, pp. 3140-3145.
Watarai et al, “Disulfide oxidoreductase activity ofShigella flexneriis required for release of Ipa proteins and invasion of epithelial cells”, Proc. Natl. Acad. Sci. U.S.A., vol. 92, 1995, pp. 4927-4931.
Peek et al, “Characterization of a periplasmic thiol:disulfide interchange protein required for the functional maturation of secreted virulence factors ofVibrio chlorae”, Proc. Natl. Acad. Sci. U.S.A., vol. 89, 1992, pp. 6210-6214.
Jonson et al, “Cloning and sequencing ofVibrio choleramannose-sensitive haemagglutinin pilin gene: localization of mshA within a cluster of type 4 pilin genes”, Molecular Microbiology, vol. 13, No. 1, 1994, pp. 109-118.
Van der Ley et al, “Construction ofNeisseria meningitidisstrains carrying multiple chromosomal copies of the porA gene for use in the production of a multivalent outer membrane vesicle vaccine”, Vaccine, vol. 13, No. 4, 1995, pp. 401-407.
Scheuerpflug et al, “Roles of PilC and PilE proteins in pilus-mediated adherence ofNeisseria gonorrhoeaandNeisseria meningitidisto human erythrocytes and endothelial and epithelial cells”, Infection and Immunity, vol. 67, No. 2, Feb. 1999, pp. 834-843.
Stibitz et al, “Genetic analysis of a region of theBordetella pertussischromosome encoding filamentous hemagglutinen and the pleiotropic regulatory locus vir”, Journal of Bacteriology, vol. 170, No. 7, Jul. 1988, pp. 2904-2913.
Virji et al, “Variations in the expression of pili: the effect on adherence ofNeisseria meningitidisto human epithelial and endothelial cells”, Molecular Microbiology, GB, Oxford, vol. 6, No. 10, 1992, pp. 1271-1279.
Zhou et al, “Sequence diversity within the argF, fbp and recA genes of natural isolates ofNeisseria meningitidis: interspecies recombination within the argF gene”, Molecular Microbiology, vol. 6, No. 15, 1992, pp. 2135-2146.
Barenkamp et al, “Cloning, Expression, and DNA Sequence Analysis of Genes Encoding NontypeableHaemophilus influenzaeHigh-Molecular-Weight Surface-Exposed Proteins Related to Filamentous Hemagglutinin ofBordetella pertussis”, Inflection and Immunity, US, American Society for Microbiology, Washington, vol. 60, No. 4, Apr. 1, 1992, pp. 1302-1313.
Salit et al, “Adherence ofNeisseria meningitidisto human epithelial cells”, Infection and Immunity, vol. 31, No. 1, Jan. 1981, pp. 430-435.
EMBL databases; Heidelberg, Germany, May 18, 1999, “Neisseria meningitidisNatD (natD) and NatC (natC) genes, complete cds.”, abstract.
Stone et al, “Salmonella enteritidishas a homologue of tolC that is required for virulence in BALB/c mice”, Molecular Microbiology, vol. 17, No. 4, 1995, pp. 701-712.

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