Negatively charged polymeric electret implant

Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Implantable prosthesis – Bone

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623 11, 623 22, 433173, 4332011, A61F 228

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057592055

ABSTRACT:
A biocompatible implant having improved host tissue ingrowth capability and enhanced blood compatibility comprises at least one tissue-contacting surface of an electrically charged material. The electrically charged material can be further chemically modified with covalently bonded activator molecules which further promote host tissue ingrowth and adhesion to the implant and/or enhance blood compatibility.

REFERENCES:
patent: 3609768 (1971-10-01), Ayres
patent: 3723754 (1973-03-01), Murayama et al.
patent: 3968790 (1976-07-01), Fukada et al.
patent: 3992725 (1976-11-01), Honsy
patent: 4202055 (1980-05-01), Reiner et al.
patent: 4268653 (1981-05-01), Uchidoi et al.
patent: 4668449 (1987-05-01), Soni et al.
patent: 4738740 (1988-04-01), Pinchuk et al.
patent: 4789634 (1988-12-01), Muller-Lierheim et al.
patent: 4795475 (1989-01-01), Walker
patent: 4828563 (1989-05-01), Muller-Liekheim
patent: 4836884 (1989-06-01), McAuslan
patent: 4919659 (1990-04-01), Horbett et al.
patent: 4946903 (1990-08-01), Gardelia, Jr. et al.
patent: 4988358 (1991-01-01), Eppley et al.
patent: 5030225 (1991-07-01), Aebischer et al.
patent: 5061750 (1991-10-01), Feijan et al.
patent: 5085632 (1992-02-01), Ikada et al.
patent: 5092871 (1992-03-01), Aebischer et al.
patent: 5164187 (1992-11-01), Constantz et al.
patent: 5266309 (1993-11-01), Gardella, Jr. et al.
patent: 5298602 (1994-03-01), Shikinami et al.
patent: 5306311 (1994-04-01), Stone et al.
patent: 5311884 (1994-05-01), Scopelianos
Aebischer, P. et al., "Piezoelectric guidance channels enhance regeneration in the mouse sciatic nerve after axotomy" Brain Research, vol. 436, pp. 165-168, 1987.
Bening, R.C., "Surface Modification of Poly(tetrafluoroethylene-co-hexafluoropropylene). Introduction of Alcohol Functionality" Macromolecules, vol. 23, pp. 2648-2655, 1990.
Davies, J.E., "The Importance and Measurement of Surface Charge Species in Cell Behaviour at the Biomaterial Interface" in Surface Characterization of Biomaterials, B.D. Ratner (ed.), pp. 219-234, Amsterdam: Elsevier Science Publishers B.V., 1988.
DeRossi, D.E. et al., "The Electromechanical Connection: Piezoelectric Polymers in Artificial Organs" ASAIO (Reprint), vol. 6, No. 1, pp. 1-11, 1983.
Fukada, E., Piezoelectricity of Bone and Osteogenesis by Piezoelectric Films, in Mechanisms of Growth Control, R.O. Becker and C.C. Thomas (eds.), pp. 192-210, 1981.
Inoue, S. et al., "Electric Stimulation of Osteogenesis in the Rat: Amperage of Three Different Stimulation Methods" in Electrical Properties of Bone and Cartilage, C.T. Brighton, J. Black and S. Pollack (eds.), pp. 199-213, Grune & Stratton, 1979.
Lovinger, A.J., "Ferroelectric Polymers" Science, vol. 220, No. 4602, pp. 1115-1121, 1983.
Pierschbacher, M.D. and E. Ruoslahti, "Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecules" Nature, vol. 309, pp. 30-33, 1984.
Ruoslahti, E. and M.D. Perschbacher, "New Perspectives in Cell Adhesion: RGD and Integrins" Science, vol. 238, pp. 491-497, 1987.
Shelton, R.M. and J.E. Davies, "Osteoblast Reactions to Charged Polymers" in The Bone-Biomaterial Interface; J.E. Davies (ed.), pp. 181-198, Toronto: U. Toronto Press, 1991.
Shoichet, M. and T.J. McCarthy, "Surface Modification of Poly (tetrafluoroethylene-co-hexafluoropropylene) Film by Adsorption of Poly(L-lysine) from Aqeusous Solution" Macromolecules, vol. 24, pp. 1441-1442, 1991.
Valentini, R.F. et al., "Electrically charged polymeric substrates enhance nerve fibre outgrowth in vitro" Biomaterials, vol. 13, No. 1, pp. 183-190, 1992.
Valentini, R.F. et al., "Patterned neuronal attachment and outgrowth on surface modified, electrically charged fluoropolymer substrates" J. Biomater. Sci., Polymer Edn., vol. 5, Nos. 1 & 2, pp. 13-36, 1993.
Valentini, R.F. et al., "Polymer electret guidance channels enhance peripheral nerve regeneration in mice" Brain Research, vol. 480, pp. 300-304, 1989.

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