Negative contrast agents for magnetic resonance imaging comprisi

Details Negative contrast agents for magnetic resonance imaging comprisi Negative contrast agents for magnetic resonance imaging comprisi

1993-05-20

1995-06-13

Hollinden, Gary E.

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Magnetic imaging agent

436173, 424684, 424709, A61B 5055

Patent

active

054241421

ABSTRACT:
A negative contrast agent for MRI is an aqueous suspension having a quantity of barium sulfate between 25 and 30 percent by weight and a quantity of bentonite between 2.5 and 3.5 percent by weight and between 0.15 and 0.25 mM Fe as a ferrite. Such a negative contrast agent provides substantially black imaging in a T2 weighted pulse sequence; namely a relative signal intensity (RSI) of near zero. It also provides a relative signal intensity (RSI) of well under 10 percent of that of water in a T1 weighted pulse sequence.

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patent: 4916170 (1990-04-01), Nambu et al.
patent: 5205290 (1993-04-01), Unger
patent: 5277896 (1994-01-01), Balkus, Jr.

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