Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Patent
1999-04-26
2000-11-07
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
424464, 424474, 424480, 514252, 51425503, 514384, A61K 922, A61K 928, A61K 31495, A61K 314196
Patent
active
06143325&
ABSTRACT:
Extended-release nefazodone compositions containing nefazodone hydrochloride, ionic and non-ionic gelling polymers, an insoluble hydrophilic agent, and optional pharmaceutically acceptable excipients demonstrate pH-modulated release of nefazodone. These compositions are formulated into unit dosage forms for improved oral administration. The improvements comprise an extended drug release profile providing comparative levels of nefazodone with respect to immediate release dosage forms and, additionally, demonstrating the lack of a food effect.
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Dennis Andrew B.
Hodsdon Alison C.
Timmins Peter
Bristol--Myers Squibb Company
Page Thurman K.
Pulliam Amy E
Ryan Richard P.
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