Surgery – Means for introducing or removing material from body for... – Treating material introduced into or removed from body...
Reexamination Certificate
2002-01-11
2009-06-16
Sirmons, Kevin C (Department: 3767)
Surgery
Means for introducing or removing material from body for...
Treating material introduced into or removed from body...
C604S072000
Reexamination Certificate
active
07547292
ABSTRACT:
A method of distributing particles in a flow of gas and a needleless syringe for use in the needleless injection of particles into the skin or mucosa of a vertebrate subject are disclosed. The syringe includes a convergence which reduces pressure of the gas flowing in the gas flow path due to the Venturi effect such that particles initially located outside of the gas flow path are drawn into the gas flow path under the action of the reduced pressure and become entrained in the gas. An exit nozzle accelerates the particles so entrained. In another aspect of the invention, there is provided a method of creating a gas flow in a needleless syringe which comprises flowing gas through a first convergence into a chamber to form a transsonic gas jet in the chamber and passing the gas jet from the chamber into a second convergence and along the nozzle.
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Yu Xinglong et al.: “Particle Acceleration for Delivery Deoxyribonucleic Acid Vaccine into Skin In Vivo”, Review of Scientific Instruments, Aug. 2001, pp. 3390-3395, vol. 72, No. 8, American Institute of Physics.
Bellhouse Brian John
Costigan George
Sheldrake Colin David
Foley & Lardner LLP
Gilbert Andrew M
Powderject Research Limited
Sirmons Kevin C
LandOfFree
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