Needle electrodes for mediated delivery of drugs and genes

Details Needle electrodes for mediated delivery of drugs and genes Needle electrodes for mediated delivery of drugs and genes

1995-06-06

1997-12-30

Bockelman, Mark

Surgery

Means for introducing or removing material from body for...

Infrared, visible light, ultraviolet, x-ray or electrical...

607116, A61N 130

Patent

active

057023590

ABSTRACT:
An electrode apparatus for the application of electroporation to a portion of the body of a patient, comprises a support member, a pair of electrodes adjustably mounted on the support member for movement toward and away from one another for positioning on opposite sides of a body portion to be electroporated, a sensing element for sensing a distance between the electrodes and generating a distance signal proportionate to the distance between said electrodes, and means responsive to said distance signal for applying pulses of high amplitude electric signal to the electrodes proportionate to the distance between said electrodes.

REFERENCES:
patent: 1099062 (1914-06-01), Laposkey
patent: 4955378 (1990-09-01), Grasso
patent: 5019034 (1991-05-01), Weaver et al.
patent: 5058605 (1991-10-01), Slovak
patent: 5128257 (1992-07-01), Baer
patent: 5273525 (1993-12-01), Hofmann
patent: 5389069 (1995-02-01), Weaver

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