Needle assembly for use in delivering precise dosages of...

Surgery – Means for introducing or removing material from body for... – Treating material introduced into or removed from body...

Reexamination Certificate

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C600S585000, C604S164010

Reexamination Certificate

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07837668

ABSTRACT:
The needle assembly of the invention is a quad-partite system for use with an arc-center stereotactic headframe that allows a clinician to deliver recombinant expression vectors through the needle assembly to targeted sites at exact depths in the brain. Methods for use of the needle assembly with a tube insert for the needle cannula that does not bind proteins, as in protein viral capsids, permit delivery of precise volumes of pharmaceutical compositions containing viral recombinant expression vectors for gene therapy.

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patent: 6683058 (2004-01-01), Tuszynski
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patent: 7060056 (2006-06-01), Palasis et al.
patent: 7071172 (2006-07-01), McCown et al.
patent: 2005/0113767 (2005-05-01), Palasis et al.
patent: 2005/0261234 (2005-11-01), Dorey et al.
patent: 2006/0135945 (2006-06-01), Bankiewicz et al.

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