Chemistry: analytical and immunological testing – Involving producing or treating antigen or hapten – Producing labeled antigens
Reexamination Certificate
2006-08-01
2006-08-01
Ceperley, Mary E. (Department: 1641)
Chemistry: analytical and immunological testing
Involving producing or treating antigen or hapten
Producing labeled antigens
C435S006120, C435S007210, C435S007320, C435S007500, C436S500000, C436S800000, C436S815000, C436S817000
Reexamination Certificate
active
07083986
ABSTRACT:
A method for the detection or quantitation of an analyte in a biological sample is disclosed. The method comprises the steps of selecting a biological sample suspected of containing a target analyte and binding the target analyte in the sample to a binding partner conjugated to an acridinium compound, wherein the acridinium compound comprises an acridinium nucleus having an electron-donating substituent directly attached to the acridinium nucleus at the C2position. Chemiluminescent acridinium compounds useful in the method have emission maxima close to or in the near infrared (NIR) region (>590 nm). These chemiluminescent acridinium compounds when used in conjunction with short wavelength-emitting acridinium esters (with emission maxima below 450 nm) can be highly useful labels for the simultaneous detection of multiple target analytes in a single assay.
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Jiang Qingping
Law Say-Jong
Natrajan Anand
Sharpe David
Bayer Healthcare LLC
Ceperley Mary E.
Sen Rupa
Weingarten Schurgin, Gagnebin & Lebovici LLP
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