Natural pulmonary surfactant, method of preparation and pharamce

Details Natural pulmonary surfactant, method of preparation and pharamce Natural pulmonary surfactant, method of preparation and pharamce

1988-04-05

1991-06-18

Schain, Howard E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

424557, 514 2, 514 78, 514975, 520350, 520359, A61K 3722, A61K 31685

Patent

active

050249959

ABSTRACT:
A pulmonary surfactant of animal origin made up of a high percentage of phospholipids (.perspectiveto.99%), by a protein fraction and characterized by the absence of carbohydrates and cholesterol.
The surfactant of the invention, obtained through filtration, centrifugation and extraction and by chromatography in inverse phase, allows better therapeutic results in the treatment of infant and adult respiratory distress syndromes (IRDS and ARDS).

REFERENCES:
patent: 4312860 (1982-01-01), Clements
patent: 4338301 (1982-07-01), Tetsuro et al.
patent: 4397839 (1983-08-01), Tanaka
patent: 4603124 (1986-07-01), Takei et al.
patent: 4765987 (1988-08-01), Bonte et al.

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