Natural, non-allergenic, immune system stimulant

Details Natural, non-allergenic, immune system stimulant Natural, non-allergenic, immune system stimulant

2001-06-21

2002-10-22

Webman, Edward J. (Department: 1617)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Conjugate or complex

C514S885000, C514S783000, C424S451000, C424S464000, C424S489000

Reexamination Certificate

active

06468541

ABSTRACT:

FIELD OF THE INVENTION
This invention relates to dietary supplements. More particularly, this invention relates to supplements which will stimulate the immune system without producing an allergic response.
BACKGROUND OF THE INVENTION
Recently, evidence has been accumulating that herbal supplements, taken regularly, may have beneficial effects. Herbal supplements, unlike medicines, are not effective instantaneously but must be taken over long periods of time in order to be effective. In other words, it takes time to create an effect in humans. There are many products on the market that claim to stimulate the immune system but the research behind such products seems to be borderline at best. See article on functional food to be published in California agriculture 2000, probably in November 2000 issue. Stimulating the immune system is a perfect application for herbal supplements because the immune system can be improved gradually. An improved immune system can be beneficial in fighting all kinds of illnesses from the common cold to deadly cancers.
Unfortunately, many herbal supplements can create an allergic response in humans. What is needed is a dietary supplement or herbal supplements that can stimulate the human immune system without inducing an allergic response. It is also important that this product have been properly tested for efficacy. Development of an herbal supplement that can stimulate the immune system without producing an allergic response presents a great improvement in the field of medicine and satisfies a long felt need of medical practitioners and of their patients.
SUMMARY OF THE INVENTION
In detail, the invention concerns an immune system stimulator compositions comprising Hericium, Radix Astragali,
Cordyceps Sinensus,
Radix Glycyrrhizae and
Dioscoreae Oppositae.
The invention particularly concerns such immune system stimulator compositions wherein the compositions comprise 5-80% by weight Hericium, 5-40% by weight Radix Astragali, 5-40% by weight
Cordyceps Sinensus,
1-40% by weight Radix Glycyrrhizae and 5-40% by weight
Dioscoreae Oppositae,
and more particularly, The immune system stimulator of claim 1, wherein said stimulator comprises 40-70% by weight Hericium, 10-50% by weight Radix Astragali, 5-30% by weight
Cordyceps Sinensus,
1-30% by weight Radix Glycyrrhizae and 5-30% by weight
Dioscoreae Oppositae.
The invention is particularly concerned with embodiments of such compositions, wherein all ingredients are powdered, and/or wherein a biologically effective amount of the ingredients are present in a biologically effective amount per dose (preferably containing 100 mg total amount per dose).
The invention is particularly concerned with embodiments of the above compositions in which a biologically effective amount of the ingredients are incorporated into a pill, a capsule, or a gel cap (preferably containing 100 mg total amount per dose).
The invention additionally concerns a method of making an immune system stimulator comprising the steps of:
(a) obtaining powdered Hericium, Radix Astragali,
Cordyceps Sinensus,
Radix Glycyrrhizae, and
Dioscoreae Oppositae;
and
(b) mixing 5-80% by weight Hericium, 5-40% by weight Radix Astragali, 5-40% by weight
Cordyceps Sinensus,
1-40% by weight Radix Glycyrrhizae and 5-40% by weight
Dioscoreae Oppositae
together.
The invention is particularly concerned with embodiments of the above methods wherein method further comprises formulating biologically effective amounts of the ingredients of the mixture into a pill, a capsule, or a gel cap (preferably containing 100 mg total amount per dose).
The invention further provides a method of stimulating the immune system of a human or other mammal comprising providing to the human or other mammal a biologically effective amount of an immune system stimulator comprising Hericium, Radix Astragali,
Cordyceps Sinensus,
Radix Glycyrrhizae and
Dioscoreae Oppositae.
The invention particularly concerns the embodiment of such method wherein the stimulator comprises a biologically effective amount of an immune system stimulator comprising 5-80% by weight Hericium, 5-40% by weight Radix Astragali, 5-40% by weight
Cordyceps Sinensus,
1-40% by weight Radix Glycyrrhizae and 5-40% by weight
Dioscoreae Oppositae,
and more particularly, wherein the stimulator comprises 40-70% by weight Hericium, 10-50% by weight Radix Astragali, 5-30% by weight
Cordyceps Sinensus,
1-30% by weight Radix Glycyrrhizae and 5-30% by weight
Dioscoreae Oppositae.
The invention particularly concerns the embodiment of such method wherein the biologically effective dose comprises 100 mg.


REFERENCES:
patent: 1102113 (1995-05-01), None
patent: 1133189 (1996-10-01), None
patent: 1147917 (1997-04-01), None
Chevallier, A. The Encyclopedia of Medicinal Plants. 1996. DK. pp. 65, 99, 200 and 215.*
Gennaro et al. Remington's Pharmaceutical Sciences. 1990. Mack. Ed. 18th. pp. 1294-1295.*
Mao et al., “Effects of a Combination of Traditional Chinese Botanicals (Immune°) on the Secretion of Interleukin-1&bgr; and Interferon-y by Peripheral Blood Polynuclear Cells,” (J. Med. Food4(1):1-7 (2001).
Arase, Y., Ikeda, K., Murashima, N., Chayama, K., Tsubota, A., Koida, I., Suzuki, Y., Saitoh, S., Kobayashi, M. and Kumada, H. (1997). The long term efficacy of glycyrrhizin in chronic hepatitis C patients. Cancer 79, 1494-1500.
Boehm, U., Klamp, T., Groot, M. and Howard, J. (1997). Cellular responses to interferon-g. Annu Rev Immunol 15, 749-795.
Cassidy, C.M. (1998). Chinese medicine users in the United States part I: utilization, satisfaction, medical plurality. J. Alt. Comp. Med. 4, 17-27.
Cassidy, C.M. (1998). Chinese medicine users in the United States part II: preferred aspects of care. J. Alt. Comp. Med. 4, 189-202.
Choate, C.J., “Modern Medicine and Traditional Chinese Medicine,” J. Chinese Med. 60, 27-36 (1999).
Chu, D.T., Lepe-Zuniga, J., Wong, W.L., LaPushin, R. and Mavligit, G.M. (1988). Fractionated extract ofAstragalus membranaceus, a Chinese medicinal herb, potentiates LAK cell cytotoxicity generated by a low dose of recombinant interleukin-2. J Clin Lab Immunol 26, 183-187.
Chu, D.T., Wong, W.L. and Mavligit, G.M. (1988). Immunotherapy with Chinese medicinal herbs. II. Reversal of cyclophosphamide-induced immune suppression by administration of fractionatedAstragalus membranaceusin vivo. J Clin Lab Immunol 25, 125-129.
Eisenberg, D.M., Davis, R.B., Ettner, S.L., Appel, S., Wilkey, S., Van Rompay, M. and Kessler, R.C. (1998). Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national survey. JAMA, J. Am. Med. Assoc. 280, 1569-1575.
Eisenberg, D.M., Kessler, R.C., Foster, C., Norlock, F.E., Calkins, D.R. and Delbanco, T.L. (1993). Unconventional medicine in the United States: prevalence, costs, and patterns of use. N. Engl. J. Med. 328, 246-252.
Jin, R. and Kurashige, S. (1996). Effects of Chinese herbs on macrophage functions in N-butyl-N-butanolnitrosoamine treated mice. Immunopharmacol Immunotoxical 18, 105-114.
Jiezhong, X., “Senile Dimentia Experience in Treatment According to Differentiation of Patterns,” J. Chinese Med. 53, 9-13 (1997).
Kobayashi, M., Herndon, D.N., Pollard, R.B. and Suzuki, F. (1995). CD4+ contrasuppressor T cells improve the resistance of thermally injured mice infected with HSV. J Leukoc Biol 58, 159-167.
Kobayashi, M., Schmitt, D.A., Utsunomiya, T., Pollard, R.B. and Suzuki, F. (1993). Inhibition of burn-associated suppressor cell generation by glycyrrhizin through the induction of contrasuppressor T cells. Immunol Cell Biol 71, 181-189.
Kuo, Y.C., Tsai, W.J., Shiao, M.S., Chen, C.F. and Lin, C.Y. (1996). Cordyceps sinensis as an immunomodulatory agent. Am J Chin Med 24, 111-125.
Kurashige, S., Akuzawa, Y. and Endo, F. (1999). Effects of astragali radix extract on carcinogenesis, cytokine production, and cytotoxicity in mice treated with a carcinogen, N-butyl-N'-butanolnitrosoamine. Cancer Invest 17, 30-35.
Lu et al., “Effect of Zi Gui Decoction on Immune Function in 60Co gamma-irradiated mice,” Zhonghua Fangshe Y

Affiliated with

Also associated with

Rating

Natural, non-allergenic, immune system stimulant does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Natural, non-allergenic, immune system stimulant, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Natural, non-allergenic, immune system stimulant will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2997763