Native calcitonin mimetics

Details Native calcitonin mimetics Native calcitonin mimetics

1995-04-04

1997-12-16

Davenport, Avis M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530307, 530326, A61K 3800, C07K 500, C07K 700

Patent

active

056985215

ABSTRACT:
The invention provides isolated, biologically active native calcitonin mimetics and related methods. These small 16 and 17 amino acid proteins mimic the interaction of calcitonin on its receptor, and also exhibit bone resorptive inhibiting activity.

REFERENCES:
Yates, et al., Endocrinology 126 (6): 2845-2849, 1990.
Orlowski et al., Eur. J. Biochem. 162: 399-402, 1987.
Rinehart et al., J. Am. Chem. Soc. 103: 6517-6520, 1981.
Moe et al., Biochemistry 24: 1971-1976, 1985.

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