Nasally administrable peptide compositions on hydroxyapatite car

Details Nasally administrable peptide compositions on hydroxyapatite car Nasally administrable peptide compositions on hydroxyapatite car

1994-10-18

1996-11-12

Russel, Jeffrey E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

424499, 514 2, 514 12, 514 21, 514770, 519784, 519951, 519970, A61K 914, A61K 3823, A61K 3828, A61K 4702

Patent

active

055740065

ABSTRACT:
A physiologically active peptide composition having a physiologically active peptide dispersed homogeneously in and adsorbed homogeneously onto a unique carrier. The physiologically active peptide composition contains a physiologically effective amount of the physiologically active peptide dispersed homogeneously in and adsorbed homogeneously onto hydroxyapatite. The composition is nasally administrable in powdery form.

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Bull. Tokyo Med. Dent. Univ., vol. 25, issued 1978, Kuboki et al, "Hydroxyapatite-Reactive Salivary Protein . . . ", pp. 123-131.
Bio-Medical Materials and Engineering, vol. 4, No. 4, issued 1994, Kano et al, "Application of Hydroxyapatite Sol . . . ", pp. 283-290.
Proc. Am. Assoc. Cancer Res., vol. 35, issued Mar. 1994, Mizuno et al, "Intraperitoneal Administration of Hydroxyapatite . . . ", p. 418, Abs. No. 2491.

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