Nasally administrable compositions containing physiologically ac

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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514 3, 514 12, 514 15, 514 53, 514314, 514327, 514510, 514532, 514554, 514675, 530303, 530307, 530313, 530399, 424499, A61K 950, A61K 3803, A61K 3816

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active

059088249

ABSTRACT:
A nasally administrable composition having a physiologically active peptide dispersed homogeneously in and adsorbed homogeneously onto a unique carrier. The composition contains an effective amount of physiologically active peptide dispersed homogeneously in and adsorbed homogeneously onto a mucosa protecting and/or tissue repairing agent, e.g., gefarnate, aceglutamide aluminum, sucralfate, L-glutamine, sofalcone, teprenone, plaunotol, rebamipide, aldioxa, cetraxate or troxipide.

REFERENCES:
patent: 4613500 (1986-09-01), Suzuki et al.
patent: 5236700 (1993-08-01), Koslo et al.
patent: 5578324 (1996-11-01), Dohi et al.
patent: 5578567 (1996-11-01), Cardinaux et al.
Patent Abstracts of Japan, vol. 15, No. 317, Pub. No. JP3120229, Ab. Date Aug. (1991).
Chemical Abstracts, vol. 117, No. 16, Ab. No. 157517, Oct. (1992).
M. Mishima et al., "Promotion of Nasal Absorption of Insulin by Glycyrrhetinic Acid Derivatives", J. Pharmacobio-Dyn., vol. 12, (1989), pp. 31-36.
Budavari et al., "The Merck Index", Merck & Co., (1989).

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