Nasal melatonin composition

Details Nasal melatonin composition Nasal melatonin composition

1998-03-26

1999-12-28

Azpuru, Carlos A.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

A61F 1302

Patent

active

060078340

ABSTRACT:
A pharmaceutical composition for intranasal administration, comprising melatonin and a pharmaceutically acceptable excipient, which is effective to cause the blood plasma melatonin concentration in a human adult, receiving an amount of melatonin in the range of 50-1000 .mu.g and in a single or simultaneous intranasal administration of said composition, to reach at least X pg/ml, within 30 minutes of said administration, wherein X is equal to 5 times the amount of melatonin, expressed in .mu.g, in said single or simultaneous administration.

REFERENCES:
patent: 4407481 (1983-10-01), Bolton et al.
patent: 4819834 (1989-04-01), Thiel
patent: 5449683 (1995-09-01), Wurtman, II
Vollrath et al., Adv. Bioscience, 29 (1981), pp. 327-329.
Gennaro et al., Remington's Pharmaceutical Sciences, 18th ed., Mack Publishing Company, 1990, see Part 8: Pharmaceutical Prepar and Their Manufacture.
Database WPI, Week 8040, Derwent Publications Ltd., London, GB; AN 80-70195C '40! -XP002036405.

Affiliated with

Also associated with

Rating

Nasal melatonin composition does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Nasal melatonin composition, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nasal melatonin composition will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2380567