Nasal dosage forms of propranol

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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2604045, 26050117, 424 19, 424 35, 424362, A61K 906, A61K 31135, C07C 9300

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active

043943900

ABSTRACT:
The invention relates to a novel method of administering propranolol, a known .beta.-adrenergic blocking agent widely used in the treatment of angina pectoris, arrhythmias, hypertension and other cardiac conditions, and migraine. The invention further relates to novel dosage forms of propranolol which are adapted for nasal administration and which include solutions, suspensions, gels and ointments.

REFERENCES:
patent: 4161530 (1979-07-01), Koella
patent: 4250163 (1981-02-01), Nagai
patent: 4284648 (1981-08-01), Hussain
Black, Brit. J. Pharmacol., vol. 25, 1965, pp. 577-591.
Stern, Arzmit. Forsch., vol. 24, 1974, pp. 70-71.
Martindale, The Extra Pharm., Pharm. Press. London, 26th Ed, 1972, pp. 1582-1583.

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