Nasal compositions

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 3144

Patent

active

048853054

ABSTRACT:
Novel nasal pharmaceutical composition adapted to be absorbed systemically through the nasal mucus and comprising as active agent a calcium antagonist selected from optionally substituted, 1,4-dihydropyridines bearing in the 4 position a monocyclic ring, together with a nontoxic pharmaceutically aceptable nasal carrier therefor.

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Dittert, Sprowls' American Pharmacy, 7th Ed. (1974) p. 416.
Letters to the Editor, J. Pharm. Pharmac., 1972, 24; 917; Loev et al.
European Journal of Pharmacology, 54 (1979) 289-293 Jolly et al.
Van De Donk et al; First European Congress of Biopharmaceutics and Pharmacokinetics; pp. 406-414.
Sucken et al; Pharmazeutische Technologie, Deutschland (1978), pp. 722-729; English Translation enclosed.

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