Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active...
Patent
1997-04-01
2000-01-11
Kulkosky, Peter F.
Drug, bio-affecting and body treating compositions
Solid synthetic organic polymer as designated organic active...
514885, A61K 31765, A61K 31785
Patent
active
060132515
ABSTRACT:
The narrow poly- or mono-dispersed oligomers of the present invention are polyureas, polycarbonates, polyesters or polyamides having a recurring unit of from 3 to 50. These oligomers are water-soluble, preferably have a rigid backbone, have recurring units coupled by carbonyl linking moieties which have anionic groups, display predominantly linear geometry such that regular spacing between anionic groups exists in an aqueous medium, and are pharmaceutically-acceptable. The narrow poly- or mono-dispersed oligomers are useful for the treatment and/or diagnosis of AIDS and/or ARC or HSV.
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Cardin Alan D.
Chamberlin Thomas A.
Fazio Michael J.
Fordyce William A.
Mullins Michael J.
Kulkosky Peter F.
Merrell Pharmaceuticals Inc.
The Dow Chemical Co.
Voelk Eric K.
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