Narrow poly- and mono-dispersed anionic oligomers, and their use

Details Narrow poly- and mono-dispersed anionic oligomers, and their use Narrow poly- and mono-dispersed anionic oligomers, and their use

1992-01-09

1995-06-13

Michl, Paul R.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

514576, 514577, 514885, C09G 7102, A61K 3117, A01N 3300

Patent

active

054240638

ABSTRACT:
The narrow poly- or mono-dispersed oligomers of the present invention are polyureas, polycarbonates, polyesters or polyamides having a recurring unit of from 3 to 50. These oligomers are water-soluble, preferably have a rigid backbone, have recurring units coupled by carbonyl linking moieties which have anionic groups, display predominantly linear geometry such that regular spacing between anionic groups exists in an aqueous medium, and are pharmaceutically-acceptable. The narrow poly- or mono-dispersed oligomers are useful for the treatment and/or diagnosis of AIDS and/or ARC or HSV.

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