Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – From reactant having a nitrogen atom directly bonded to the...
Patent
1997-11-26
1999-11-16
Kulkosky, Peter F.
Synthetic resins or natural rubbers -- part of the class 520 ser
Synthetic resins
From reactant having a nitrogen atom directly bonded to the...
528370, 528391, 424 7808, 564 49, C09G 7102, A61K 3117, A61K 31795, A01N 3300
Patent
active
059860448
ABSTRACT:
The narrow poly- or mono-dispersed oligomers of the present invention are polyureas, polycarbonates, polyesters or polyamides having a recurring unit of from 3 to 50. These oligomers are water-soluble, preferably have a rigid backbone, have recurring units coupled by carbonyl linking moieties which have anionic groups, display predominantly linear geometry such that regular spacing between anionic groups exists in an aqueous medium, and are pharmaceutically-acceptable. The narrow poly- or mono-dispersed oligomers are useful for the treatment and/or diagnosis of AIDS and/or ARC or HSV.
REFERENCES:
patent: 2833744 (1958-05-01), Neher
patent: 3528949 (1970-09-01), Rutledge
patent: 4104262 (1978-08-01), Schade
patent: 4328244 (1982-05-01), Daniel et al.
patent: 4349568 (1982-09-01), Markley et al.
patent: 4736014 (1988-04-01), Engelhardt
patent: 4783446 (1988-11-01), Neushul
patent: 4824916 (1989-04-01), Kershner
patent: 4895660 (1990-01-01), Kershner
patent: 4966894 (1990-10-01), Herr et al.
patent: 5276182 (1994-01-01), Cardin et al.
patent: 5424063 (1995-06-01), Cardin et al.
patent: 5460807 (1995-10-01), Cardin et al.
patent: 5512177 (1996-04-01), Cardin et al.
patent: 5571505 (1996-11-01), Cardin et al.
patent: 5670143 (1997-09-01), Cardin et al.
patent: 5670144 (1997-09-01), Cardin et al.
Vandenberg E.J. et al., Polymeric Matericals Science and Engineering, vol. 57, Fall Meeting 1987, pp. 139-143.
Antiviral Research, 18 (1992), Sulfonic acid polymers as a new class of human immunodefi-ciency virus inhibitors, Prem Mohan, et al., pp. 139-150.
Protein Purification, 2nd Ed., Separation in Solution, Springer-Verlag, 1987, Robert K. Scopes (author, Charles R. Cantor (editor), pp. 186-215).
Polymer Fractionation, Academic Press, 1967, Manfred J.R. Cantow, Ed., pp. 43-67.
Polymer Fractionation, Academic Press, 1967, Manfred J.R. Cantow, Ed., p. 462.
Dowex:ION Exchange, 1958, The Dow Chemical Company, The Lakeside Press, pp. 39-66.
Journal of Chromatography Library, vol. 41A, 1988, High-performance liquid chromatography of biopolymers and biooligomers, O. Mikes, pp. A127-A344.
American Chemical Soc, 1982, The Antiutmor andAntiviral Effects of Polycarboxylic Acid Polymers, R.M. Ottenbrite.
Protein Purification, 1897, "Elecctrophetic Methods--Simple Electrophoresis", pp. 199-215.
Dowex:: ION Exchange, The Dow Chem. Co. 1958, 1959.
Antiviral Chem & Chemo (1995)6(1) 34-42, "Potent Inhibitionof Herpes Simplex Virus by MDL 101028, a Novel Biphenyl Disulfonic acid urea co-polymer", S.P. Ahmed, A.D. Cardin,C.G. Bridges, R.L. Jackson, M.J. Mullins and A.S. Tyms.
Chem. Abstracts, polyamides vol. 102, No. 62707 (1985)m Toshiba Corp., Japan, "Block Copolmers" JP 59179521.
Komp, et al., Chemical Abstracts vol. 110 Abstract No. 33727k (1989).
Hofferek, et al., Chemical Abstract vol. 114 Abstract No. 180333q (1990).
Berge et al., J of Pharm. Sciences (1977) 66(1), Pharmaceutical Salts, pp. 1-19.
Cardin Alan D.
Chamberlin Thomas A.
Fazio Michael J.
Fordyce William A.
Mullins Michael J.
Kulkosky Peter F.
Merrell Pharmaceuticals Inc.
The Dow Chemical Co.
Voelk Eric K.
LandOfFree
Narrow poly- and mono-dispersed anionic oligomers does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Narrow poly- and mono-dispersed anionic oligomers, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Narrow poly- and mono-dispersed anionic oligomers will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1326193