Nargenicin derivatives

Details Nargenicin derivatives Nargenicin derivatives

1981-05-04

1984-05-15

Fan, Jane I.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549268, 549 60, 548526, 548248, 548214, 548374, 548236, 548201, 548125, 548127, 548256, C07D23354, C07D40514

Patent

active

044489706

ABSTRACT:
Novel antibacterially-active analogs of the antibiotics nodusmicin and nargenicin A.sub.1. These compounds are prepared by selectively blocking active hydroxyl groups at the 9, 11 and 18 positions of nodusmicin, and the 11 and 18 positions of nargenicin A.sub.1. Antibacterially-active compounds can be used in various environments to control or eradicate susceptible bacteria. The techniques for such use are well known in the art.

REFERENCES:
patent: 4148883 (1979-04-01), Celmer et al.
patent: 4351769 (1982-09-01), Whaley et al.
patent: 4363922 (1982-12-01), Magerlein et al.
Celmer, W. C. et al., J. Am. Chem. Soc. 102, (1980), 4203-4209.
Magerlein et al., The Journal of Antibiotics, vol. 35, No. 2, p. 254-255, Feb. 1982.

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