Naphthyridines which affect IL-4 and G-CSF

Details Naphthyridines which affect IL-4 and G-CSF Naphthyridines which affect IL-4 and G-CSF

1997-06-19

1999-08-17

Dentz, Bernard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546122, 546143, A61K 31435, C07D47104

Patent

active

059394315

ABSTRACT:
Compounds of formula ##STR1## or pharmaceutically acceptable salts thereof, wherein E, Q, T, U, V, L, Z, X, W, M, Y and Y' are as set forth herein, are described. These compounds are useful as agents in the treatment of allergy, inflammation, autoimmune diseases, B-cell lymphomas, tumors, and the after effects of bone marrow transplantation.

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de Zwart et al, J. Med. Chem., 32 (1989), pp. 487-493.
de Zwart et al, J. Med. Chem., 31 (1988), pp. 716-722.
Chemical Abstracts, 61, 7 (1964), abstract 8285c.

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