Naphthylethylureas and naphthylethylthioureas

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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564 26, 564 28, 564 48, 564 52, 564 56, 514595, A61K 3117, C07C33506

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active

053859448

ABSTRACT:
A compound selected from those of formula (I): ##STR1## in which the meanings of R, R.sub.1, R.sub.2 and X are defined in the specification, and
medicinal products containing the same which are useful in treating or in preventing a disorder of the melatoninergic system.

REFERENCES:
Melatonin and the Pineal Gland-From basic science to Clinical Applications, pp. 303-310, 311-316, 117-122 (1993).
Journal of Endocrinology, vol. 1, No. 1, pp. 1-4 (1989).
Psychopharmacology 100, 222-226 (1990).
Journal of Neurosurgery 63, 321-341 (1985).
Neuropharmacology of Pineal-Secretions 8, Nos. 3-4 247-273 (1990).
Brain Research 528, 170-174 (1990).
Melatonin-Clinical Perspectives, 164-165 (1988).
Science 227, 714-720 (1985).
Clinical Endocrinology 24, 359-364 (1986).

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