Naphthylethylureas and naphthylethylthioureas

Details Naphthylethylureas and naphthylethylthioureas Naphthylethylureas and naphthylethylthioureas

1994-12-20

1995-09-12

Kumar, Shailendra

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514580, 514585, 514588, 514595, 514923, 564 52, 564 56, 564 17, 564 26, 564 28, 564 48, A61K 3117

Patent

active

054496900

ABSTRACT:
A compound selected from those of formula (I): ##STR1## in which the meanings of R, R.sub.1, R.sub.2 and X are as defined in the specification, and medicinal products containing the same which are useful in treating or in preventing a disorder of the melatoninergic system.

REFERENCES:
patent: 5385944 (1995-01-01), Lesieur et al.
patent: 5389683 (1995-02-01), Lesieur et al.
Journal of Endocrinology, vol. 1, No. 1, pp. 1-4 (1989).
Psychopharmacology 100, 222-226 (1990).
Journal of Neurosurgery 63, 321-341 (1985).
Neuropharmacology of Pineal-Secretions 8, Nos. 3-4 247-273 (1990).
Brain Research 528, 170-174 (1990).
Melatonin-Clinical Perspectives, 164-165 (1988).
Science 227, 714-720 (1985).
Clinical Endocrinology 24, 359-364 (1986).
Melatonin and the Pineal Gland--From basic science to Clinical Applications, pp. 303-310 (1993).
Melatonin and the Pineal Gland--From basic science to Clinical Applications, pp. 311-316 (1993).
Melatonin and the Pineal Gland--From basic science to Clinical Applications, pp. 117-122 (1993).
Elsevier Science Publishers B.V, 1993, "The effects of melatonin on the timing of wsleep in patients with delayed sleep phase syndrome", O. Tzischinsky, et al.

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