Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-12-08
1998-12-15
Huang, Evelyn
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514394, 514395, 546199, 5483044, 5483061, 5483064, 5483071, 5483094, 5483097, 5483101, A61K 31445, C07D21152
Patent
active
058497595
ABSTRACT:
Compounds of formula (I): ##STR1## wherein: n,
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Tidwell, R. et al., "Strategies for Anticoagulation with Synthetic Protease Inhibitors, Xa Inhibitors Versus Thrombin Inhibitors," Thrombosis Research, (1980) 19:339-349.
Sturzebecher, J. et al., "Cyclic Amides of N.alpha.-arysulfonylaminoacylated 4-amidinophenylalanine--Tight Binding Inhibitors of Thrombin," Thrombosis Research, (1983) 29:635-642.
Kikumoto, R. et al., "Selective inhibition of Thrombin by inecarboxylic Acid," Biochemistry, (1984) 23:85-90.
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Arnaiz Damian O.
Griedel Brian D.
Sakata Steven T.
Shaw Kenneth J.
Zhao Zuchun
Berlex Laboratories Inc.
Huang Evelyn
Roth Carol J.
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