Naphthalene derivatives, processes for preparing the same, and s

Details Naphthalene derivatives, processes for preparing the same, and s Naphthalene derivatives, processes for preparing the same, and s

1993-02-19

1994-08-30

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514247, 514327, 514340, 514345, 544239, 546205, 546275, 546269, 546301, 546302, 546341, 546344, 546342, 540302, 540341, 540344, 540342, 568592, 546290, 562512, A61K 3144

Patent

active

053429419

ABSTRACT:
Naphthalene derivative of the formula [I]: ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and are hydrogen atom, hydroxy group, cyclo-lower alkyloxy group, substituted or unsubstituted lower alkoxy group, or both combine each other to form lower alkylenedioxy group, R.sup.3 is substituted or unsubstituted nitrogen-containing 6-membered heterocyclic group, and groups of the formulae: --OR.sup.4 and --OR.sup.5 are the same or different and are protected or unprotected hydroxy group, processes for preparing thereof, and synthetic intermediates therefor, these compounds have excellent bronchodilating activity, and are useful in the prophylaxis and treatment of asthma.

REFERENCES:
patent: 4503061 (1985-03-01), Bristol
patent: 4590200 (1986-05-01), Cross
patent: 4661596 (1987-04-01), Kreft, III et al.
patent: 4792556 (1988-12-01), Murthy
patent: 5068394 (1991-11-01), Andree et al.
patent: 5182296 (1993-01-01), Nakai et al.
patent: 5189047 (1993-02-01), Hadley et al.
patent: 5208246 (1993-05-01), Almansa et al.
patent: 5272170 (1993-12-01), Almansa et al.
D. N. Reinhoudt et al., "A Novel Route for the Synthesis of Benzo[b]thiepins,"Tetrahedron, 30, 2431-2436 (1974).
A. Sakurai et al., "The Cyclization of Ethyl Acetoacetate and Ketones by Ammonium Acetate," Bull. Chem. Soc. Japan 41, 165-167 (1968).

Affiliated with

Also associated with

Rating

Naphthalene derivatives, processes for preparing the same, and s does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Naphthalene derivatives, processes for preparing the same, and s, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Naphthalene derivatives, processes for preparing the same, and s will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-30732