Naphthalene anti-psoriatic agents

Details Naphthalene anti-psoriatic agents Naphthalene anti-psoriatic agents

1988-11-25

1990-08-07

Shippen, Michael L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514269, 514311, 514312, 514277, 514344, 514345, 514398, 514399, 514406, 514407, 514419, 514424, 514427, 514432, 514461, 514473, 514510, 2604105, 260408, 544298, 544318, 544319, 546153, 546294, 546301, 548337, 548346, 548371, 548372, 548375, 548484, 548542, 548543, 548551, 548556, 549 23, 549 28, 549479, 560 8, 560 65, 560 73, 560105, 560108, 560139, A61K 3122, A61K 31275, A61K 31415, A61K 3144, C07C 6935, C07C12115

Patent

active

049468456

ABSTRACT:
Psoriasis in mammals is relieved by topically administering naphthalenes of the formula: ##STR1## wherein: R.sup.1 and R.sup.2 are the same and are lower alkoxy or optionally substituted phenoxy,

REFERENCES:
patent: 4466981 (1984-08-01), Jones et al.
patent: 4593120 (1986-06-01), Jones et al.
patent: 4737519 (1988-04-01), Yamashita
Breslow et al., Journal of the American Chemical Society, 1944, vol. 66, pp. 1286-1288.
Derwent Abstract No. 96916X, Japanese Kokai 76/1128932 to Takeda Chemical.
Derwent Abstract No. 92102D, Japanese Kokai 81/140943 to Takeda Chemical.
Carl Noller, Textbook of Organic Chemistry, 3rd Ed., 1966, pp. 172-177.
Gordon Jones et al., Journal of Medicinal Chemistry, 1986, vol. 29, pp. 1504-1511.

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