Naphthacene derivatives

Details Naphthacene derivatives Naphthacene derivatives

1976-06-14

1978-02-21

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated via claimed linking group, bond, chelating agent,...

536 4, 536 17, A61K 3171, C07H 1524

Patent

active

040753280

ABSTRACT:
The new naphthacene derivatives of the general formula: ##STR1## wherein A represents a single bond or a methylene group and acid addition salts thereof possess valuable anti-tumor properties. They are prepared by reaction of an acid addition salt of a strong acid of a corresponding naphthacene derivative having a ##STR2## group in the 13-position with a compound of the formula HO--CH.sub.2 --A--CH.sub.2 --OH.

REFERENCES:
patent: 3803124 (1974-04-01), Arcamone et al.
Pigman, "The Carbohydrates," 1957, Academic Press, New York, N. Y., pp. 229-231.

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