Naphathalene derivatives which bind to the EP4 receptor

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S365000, C514S364000, C514S378000, C514S411000, C546S276700, C548S450000, C548S451000, C548S181000, C548S125000, C548S247000, C548S248000

Reexamination Certificate

active

06924297

ABSTRACT:
Compounds of formula (I)and pharmaceutically acceptable derivatives thereof bind with high affinity to the EP4 receptor and are of use in the treatment or prevention of conditions such as a pain, inflammatory, immunological, bone, neurodegenerative or renal disorder.

REFERENCES:
patent: 4014899 (1977-03-01), Bowman et al.
patent: 4395417 (1983-07-01), Hall et al.
patent: 6030967 (2000-02-01), Marui et al.
patent: WO 98/25899 (1998-06-01), None
patent: WO 00/76969 (2000-12-01), None

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