Radiant energy – Ionic separation or analysis – With sample supply means
Reexamination Certificate
2005-03-15
2010-02-02
Berman, Jack I (Department: 2881)
Radiant energy
Ionic separation or analysis
With sample supply means
C250S281000, C250S282000
Reexamination Certificate
active
07655902
ABSTRACT:
This invention relates to a nanowire-assisted method for mass spectrometric analysis of a specimen. More specifically, by using nanowire which can fix a specimen and perform desorption/ionization of the specimen while effectively transferring laser energy to the specimen to be irradiated, thereby enabling to perform mass spectrometric analysis without using a matrix solution. This invention, by effectively performing desorption/ionization of a specimen using the above-mentioned nanowire, enables to effectively perform qualitative-, quantitative-, and micro-analyses of specimens as well as low molecular weighted specimens. Further, this invention enables to the typical device of mass spectrometric analysis used in MALDI-T of MS. In particular, this invention can perform mass spectrometric analysis of a specimen with molecular weight of less than 1,000 Da and perform quantitative analysis by fixing a specimen with a predetermined area.
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Choi Heon Jin
Pyun Jae Chul
Berman Jack I
Chang Hanway
Frommer & Lawrence & Haug LLP
Korea Institute of Science and Technology
Santucci Ronald R.
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