Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1996-03-20
1998-03-10
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
514103, A61K 3135, A61K 3155, A61K 3140
Patent
active
057261644
ABSTRACT:
The present invention relates to a pharmaceutical composition for the intravenous administration of the sparingly soluble staurosporin derivative N-benzoyl-staurosporin. The composition comprises the following preferred components:
a) the therpeutic agent N-benzoyl-staurosporin;
b) a polyoxyethylene/polyoxypropylene block copolymer;
c) ethanol and water as carrier liquids; and
d) purified lecithin from soybeans and
e) as water-soluble excipients glycerol and sorbitol.
REFERENCES:
patent: 5093330 (1992-03-01), Caravatti et al.
Wade et al, Handbook of Pharmaceutical Excipients Sec, Ed., The Pharmaceutical Press London, 1994, pp. 352-354.
Hoogevest Peter van
Weder Hans Georg
Ferraro Gregory D.
Ivy C. Warren
Mach D.Margaret M.
Mathias Marla J.
Novartis Corporation
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