Nanoparticulate diagnostic mixed carboxylic anhydrides as X-ray

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – X-ray contrast imaging agent

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558276, 562887, A61K 4904, C07C 6996, C07C 6368

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active

055737498

ABSTRACT:
This invention relates to methods of x-ray diagnostic imaging the blood pool, liver, spleen, and/or lymph system of a mammal comprising administering a contrast effective amount of a mixed carbonic anhydride as a contrast agent having the structure ##STR1## X is H, NR.sup.1 R.sup.2 or CONR.sup.1 R.sup.3, R.sup.1 is H or alkyl

REFERENCES:
patent: 3097228 (1963-07-01), Larsen
patent: 4607123 (1986-08-01), Schuster et al.
patent: 5318767 (1994-06-01), Liversidge et al.
Swanson et al, "Pharmaceuticals in Medical Imaging", 1990, MacMillan Publishing Company.
Chemical Abstract 149397-07-9 (1994).
Chemical Abstracts 105: 60940, 1985.

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