Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – X-ray contrast imaging agent
Patent
1994-06-24
1996-06-11
Robinson, Allen J.
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
X-ray contrast imaging agent
560 47, A61K 4904, C07C22960
Patent
active
055253288
ABSTRACT:
This invention relates to methods of x-ray diagnostic imaging the blood pool and/or lymph system of a mammal comprising administering a contrast effective amount of a particulate iodinated aroyloxy ester contrast agent having the structure: ##STR1## wherein n is an integer from 3 to 20; R.sup.1 is H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxyalkyl or acetamidoalkyl;
REFERENCES:
patent: 3097228 (1963-07-01), Larsen
patent: 3144479 (1984-08-01), Obendorf
patent: 5318767 (1994-06-01), Liversidge et al.
patent: 5318768 (1994-06-01), Illig et al.
patent: 5360604 (1994-11-01), Ruddy et al.
United States Patent Application Ser. No. 07/990,987 filed Dec. 16, 1992.
Siggins et al (J. Chem. Med. 8(5) 728-30 (1965).
Bacon Edward R.
Caulfield Thomas S.
Illig Carl R.
Osifo Irennegbe K.
Cebulak Mary C.
NanoSystems L.L.C.
Robinson Allen J.
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