Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Reexamination Certificate
2011-08-16
2011-08-16
Arnold, Ernst (Department: 1613)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
C424S729000, C424S744000, C424S748000, C424S768000, C424S776000, C514S012100, C514S102000, C514S251000, C514S263310, C514S440000, C514S561000, C514S573000
Reexamination Certificate
active
07998507
ABSTRACT:
Nanoparticulate compositions comprising at least one poorly soluble MAP kinase inhibitor and at least one surface stabilizer are described. The nanoparticulate compositions have an average particle size of less than about 2000 nm. The invention also describes methods of making and using such compositions.
REFERENCES:
patent: 4657901 (1987-04-01), Ueda et al.
patent: 4783484 (1988-11-01), Violante et al.
patent: 4826689 (1989-05-01), Violanto et al.
patent: 4997454 (1991-03-01), Violante et al.
patent: 5024843 (1991-06-01), Kuczynski et al.
patent: 5118528 (1992-06-01), Fessi et al.
patent: 5145684 (1992-09-01), Liversidge et al.
patent: 5298262 (1994-03-01), Na et al.
patent: 5302401 (1994-04-01), Liversidge et al.
patent: 5318767 (1994-06-01), Liversidge et al.
patent: 5326552 (1994-07-01), Na et al.
patent: 5328404 (1994-07-01), Bacon
patent: 5336507 (1994-08-01), Na et al.
patent: 5340564 (1994-08-01), Illig et al.
patent: 5346702 (1994-09-01), Na et al.
patent: 5349957 (1994-09-01), Yudelson
patent: 5352459 (1994-10-01), Hollister et al.
patent: 5399363 (1995-03-01), Liversidge et al.
patent: 5401492 (1995-03-01), Kellar et al.
patent: 5429824 (1995-07-01), June
patent: 5447710 (1995-09-01), Na et al.
patent: 5451393 (1995-09-01), Liversidge et al.
patent: 5466433 (1995-11-01), Bacon et al.
patent: 5466440 (1995-11-01), Ruddy et al.
patent: 5470583 (1995-11-01), Na et al.
patent: 5472683 (1995-12-01), Illig
patent: 5494683 (1996-02-01), Liversidge et al.
patent: 5500204 (1996-03-01), Osifo
patent: 5503723 (1996-04-01), Ruddy et al.
patent: 5510118 (1996-04-01), Bosch et al.
patent: 5518187 (1996-05-01), Bruno et al.
patent: 5518738 (1996-05-01), Eickhoff et al.
patent: 5521218 (1996-05-01), Osifo
patent: 5525328 (1996-06-01), Bacon et al.
patent: 5534270 (1996-07-01), De Castro
patent: 5543133 (1996-08-01), Swanson et al.
patent: 5552160 (1996-09-01), Liversidge et al.
patent: 5560931 (1996-10-01), Eickhoff et al.
patent: 5560932 (1996-10-01), Bagchi et al.
patent: 5565188 (1996-10-01), Wong et al.
patent: 5569448 (1996-10-01), Wong et al.
patent: 5571536 (1996-11-01), Eickhoff et al.
patent: 5573749 (1996-11-01), Illig
patent: 5573750 (1996-11-01), Singh
patent: 5573783 (1996-11-01), Desieno et al.
patent: 5580579 (1996-12-01), Ruddy et al.
patent: 5585108 (1996-12-01), Ruddy et al.
patent: 5587143 (1996-12-01), Wong
patent: 5591456 (1997-01-01), Franson et al.
patent: 5593657 (1997-01-01), Ruddy et al.
patent: 5603916 (1997-02-01), Singh
patent: 5622938 (1997-04-01), Wong
patent: 5628981 (1997-05-01), Liversidge et al.
patent: 5643552 (1997-07-01), Illig
patent: 5662883 (1997-09-01), Bagchi et al.
patent: 5665330 (1997-09-01), Wong
patent: 5665331 (1997-09-01), Bagchi et al.
patent: 5668196 (1997-09-01), Robinson et al.
patent: 5670136 (1997-09-01), Bacon et al.
patent: 5716642 (1998-02-01), Bagchi et al.
patent: 5718388 (1998-02-01), Czekai et al.
patent: 5718919 (1998-02-01), Ruddy et al.
patent: 5741522 (1998-04-01), Violante et al.
patent: 5747001 (1998-05-01), Wiedmann et al.
patent: 5776496 (1998-07-01), Violante et al.
patent: 5834025 (1998-11-01), De Garavilla et al.
patent: 5862999 (1999-01-01), Czekai et al.
patent: 6045829 (2000-04-01), Liversidge et al.
patent: 6068858 (2000-05-01), Liversidge et al.
patent: 6117455 (2000-09-01), Takada et al.
patent: 6153225 (2000-11-01), Lee et al.
patent: 6165506 (2000-12-01), Jain et al.
patent: 6221400 (2001-04-01), Liversidge et al.
patent: 6264922 (2001-07-01), Wood et al.
patent: 6267989 (2001-07-01), Liversidge et al.
patent: 6270806 (2001-08-01), Liversidge et al.
patent: 6316029 (2001-11-01), Jain et al.
patent: 6375986 (2002-04-01), Ryde et al.
patent: 6383471 (2002-05-01), Chen et al.
patent: 6428814 (2002-08-01), Bosch
patent: 6431478 (2002-08-01), Reed et al.
patent: 6432381 (2002-08-01), Liversidge et al.
patent: 6592903 (2003-07-01), Ryde et al.
patent: 2002/0012675 (2002-01-01), Jain et al.
patent: 0 275 796 (1995-09-01), None
patent: 0 499 299 (2002-08-01), None
patent: 9-271658 (1997-10-01), None
patent: WO 96/25918 (1996-08-01), None
patent: WO 98/07414 (1998-02-01), None
patent: WO 9827098 (1998-06-01), None
patent: WO 98/35666 (1998-08-01), None
patent: WO 98/51825 (1998-11-01), None
patent: WO 00/12124 (2000-03-01), None
patent: WO 00/18374 (2000-04-01), None
patent: WO 00/18374 (2000-04-01), None
patent: WO 00/23072 (2000-04-01), None
patent: WO 00/27363 (2000-05-01), None
patent: WO 01/17546 (2001-03-01), None
patent: WO 02/098565 (2002-12-01), None
Cobb et al., “MAP Kinase Signaling Pathways,”Promega Notes Magazine(1996), No. 59, p. 37, http://www.promega.com/pnotes/59/5644f/5644f.html.
Hoshino et al., “Constitute activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors,”Oncogene(1998), vol. 18, pp. 813-822.
Sebolt-Leopold et al., “Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo,”Nature Medicine(Jul. 1999), vol. 5, No. 7, pp. 810-816.
Jiang et al., Characterization of the Structure and Function of a New Mitogen-activated Protein Kinase (p38β),The Journal of Biological Chemistry(1996), vol. 271, No. 30, pp. 17920-17926.
Frantz et al., “The Activation State of p38 Mitogen-Activated Protein Kinase Determines the Efficiency of ATP Competition for Pyridinylimidazole Inhibitor Binding,”Biochemistry(1998), vol. 37, pp. 13846-13853.
Nemoto et al., “Induction of Apoptosis by SB202190 through Inhibition of p38β Mitogen-activated Protein Kinase,”The Journal of Biological Chemistry(1998), vol. 273, No. 26, pp. 16415-16420.
Davies et al., “Specificity and mechanism of action of some commonly used protein kinase inhibitors,”Biochem J.(2000), vol. 351, pp. 95-105.
www.Tocris.com, SB 202190, 2006.
Notice of Rejections from related Japanese Patent Application No. 2003-577854 dated Sep. 14, 2009.
Bosch H. William
Cary Greta G.
Hovey Douglas C.
Jain Rajeev A.
Kline Laura J.
Arnold Ernst
Elan Pharma International Ltd.
Foley & Lardner LLP
Lea Christopher R
LandOfFree
Nanoparticulate compositions of mitogen-activated protein... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Nanoparticulate compositions of mitogen-activated protein..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nanoparticulate compositions of mitogen-activated protein... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2681264